Featured Publications
Metabolic signatures of regulation by phosphorylation and acetylation
Smith K, Shen F, Lee H, Chandrasekaran S. Metabolic signatures of regulation by phosphorylation and acetylation. IScience 2022, 25: 103730. PMID: 35072016, PMCID: PMC8762462, DOI: 10.1016/j.isci.2021.103730.Peer-Reviewed Original ResearchPosttranslational modificationsTarget of phosphorylationGenome-scale metabolic networksRational rewiringRegulatory circuitsMammalian cellsCellular metabolismMetabolic networksPhosphorylated enzymeMetabolic regulationPhosphoproteome datasetEnzyme propertiesPhosphorylationAcetylationMetabolic signaturesRegulationAcetylomeTranscriptomeDiverse conditionsProteomePhosphoproteomicsTargetCondition-specific factorsEssentialityOrganisms
2017
A Topical Report on the Design Principles of Metabolism
Halbrook C, Lee H, Cantley L, Lyssiotis C. A Topical Report on the Design Principles of Metabolism. 2017, 29-44. DOI: 10.1007/978-3-319-61401-4_2.Peer-Reviewed Original Research