2023
Donor Mesenchymal Stem Cells Program Bone Marrow, Altering Macrophages, and Suppressing Endometriosis in Mice
Habata S, Mamillapalli R, Ucar A, Taylor H. Donor Mesenchymal Stem Cells Program Bone Marrow, Altering Macrophages, and Suppressing Endometriosis in Mice. Stem Cells International 2023, 2023: 1598127. PMID: 37545483, PMCID: PMC10403325, DOI: 10.1155/2023/1598127.Peer-Reviewed Original ResearchBone marrowMesenchymal stem cellsBM transplantsEndometriotic lesionsM2 macrophagesBone marrow-derived inflammatory cellsTumor necrosis factor alphaImmune system contributionsDonor mesenchymal stem cellsProportion of M1Infiltration of macrophagesDevelopment of endometriosisNecrosis factor alphaNew therapeutic targetsRecipient bone marrowReal-time polymerase chain reactionQuantitative real-time polymerase chain reactionEndometriotic lesion developmentInflammatory markersEndometrial tissueInflammatory cellsRecipient micePolymerase chain reactionInflammatory responseFluorescence-activated cell sorting
2011
Derivation of Insulin Producing Cells From Human Endometrial Stromal Stem Cells and Use in the Treatment of Murine Diabetes
Santamaria X, Massasa EE, Feng Y, Wolff E, Taylor HS. Derivation of Insulin Producing Cells From Human Endometrial Stromal Stem Cells and Use in the Treatment of Murine Diabetes. Molecular Therapy 2011, 19: 2065-2071. PMID: 21878900, PMCID: PMC3222529, DOI: 10.1038/mt.2011.173.Peer-Reviewed Original ResearchConceptsHuman endometrial stromal stem cellsStromal stem cellsPancreatic islet cell transplantationStem cellsIslet cell transplantationType 1 diabetesBlood glucose levelsTreatment of murineDifferentiated cellsDiabetic miceCell transplantationKidney capsuleCadaveric donorsPotential therapeutic applicationsProgressive hyperglycemiaInsulin secretionMurine modelGlucose levelsUterine endometriumMesenchymal stem cellsΒ-cell markersInsulinHuman insulinGlucose-responsive mannerControl cells