Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer
Flores LM, Kindelberger DW, Ligon AH, Capelletti M, Fiorentino M, Loda M, Cibas ES, Jänne PA, Krop IE. Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer. British Journal Of Cancer 2010, 102: 1495-1502. PMID: 20461092, PMCID: PMC2869174, DOI: 10.1038/sj.bjc.6605676.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsFemaleFluorescent Antibody TechniqueGene AmplificationGenes, erbB-2HumansImmunomagnetic SeparationIn Situ Hybridization, FluorescenceNeoplastic Cells, CirculatingConceptsHuman epidermal growth factor receptor 2Tumor cellsHER2 amplificationBreast cancerCTC yieldEpidermal growth factor receptor 2Growth factor receptor 2Breast cancer patientsSignificant discordance existsFactor receptor 2Lung cancer samplesMedian cell countMetastatic tumor cellsCancer patientsLung cancerMetastatic breastMetastatic tumorsPatient CTCsMetastatic cancerMetastatic tissuesBlood samplesReceptor 2Drug AdministrationCell countPatients