2022
Do Cost Limitations of Extended Prophylaxis After Surgery Apply to Ulcerative Colitis Patients?
Leeds IL, Canner JK, DiBrito SR, Safar B. Do Cost Limitations of Extended Prophylaxis After Surgery Apply to Ulcerative Colitis Patients? Diseases Of The Colon & Rectum 2022, 65: 702-712. PMID: 34840290, PMCID: PMC8995329, DOI: 10.1097/dcr.0000000000002056.Peer-Reviewed Original ResearchConceptsMultivariable probabilistic sensitivity analysesUlcerative colitis patientsIncremental cost-effectiveness ratioProbabilistic sensitivity analysesCost-effectiveness ratioDecision analysisColorectal surgery patientsExtended prophylaxisColitis patientsEl análisisSocietal perspectiveLifetime horizonSurgery patientsVenous thromboembolismColitis ulcerosaDecision analysis methodologyUn análisisPostoperative venous thromboembolismRange of scenariosType of thrombosisMain outcome measuresTotal costIndividual risk profileCostSensitivity analysis
2019
Cost-Benefit Limitations of Extended, Outpatient Venous Thromboembolism Prophylaxis Following Surgery for Crohn's Disease.
Leeds IL, DiBrito SR, Canner JK, Haut ER, Safar B. Cost-Benefit Limitations of Extended, Outpatient Venous Thromboembolism Prophylaxis Following Surgery for Crohn's Disease. Diseases Of The Colon & Rectum 2019, 62: 1371-1380. PMID: 31596763, PMCID: PMC6788772, DOI: 10.1097/dcr.0000000000001461.Peer-Reviewed Original ResearchConceptsVenous thromboembolism prophylaxisMultivariable probabilistic sensitivity analysesCrohn's diseaseHigh thrombotic riskProbabilistic sensitivity analysesThromboembolism prophylaxisExtended prophylaxisSurgical populationAbdominal surgeryThrombotic eventsUtility weightsSocietal perspectiveProductivity costsLifetime horizonIncremental costConventional measuresEnfermedad de CrohnPostoperative venous thromboembolismLow absolute riskHigh-risk individualsLos costosDecision tree modelDecision analysisRange of scenariosTotal costJustifying Total Costs of Extended Venothromboembolism Prophylaxis After Colorectal Cancer Surgery
Leeds IL, Canner JK, DiBrito SR, Safar B. Justifying Total Costs of Extended Venothromboembolism Prophylaxis After Colorectal Cancer Surgery. Journal Of Gastrointestinal Surgery 2019, 24: 677-687. PMID: 30945086, PMCID: PMC6776724, DOI: 10.1007/s11605-019-04206-z.Peer-Reviewed Original ResearchConceptsVTE event ratesColorectal cancer surgeryCancer surgeryDecision analysis modelEvent ratesCancer surgical patientsHigher VTE ratesHigh-risk patientsCase fatality ratePayer administrative databaseOutcomes of interestProbabilistic sensitivity analysesBackgroundCurrent guidelinesBleeding eventsExtended prophylaxisProvider uptakeVTE ratesVTE eventsMost patientsPostoperative dischargeSurgical patientsRisk stratificationAdministrative databasesClinical guidanceNational guidelines