2016
Anal cancer and intraepithelial neoplasia screening: A review.
Leeds IL, Fang SH. Anal cancer and intraepithelial neoplasia screening: A review. World Journal Of Gastrointestinal Surgery 2016, 8: 41-51. PMID: 26843912, PMCID: PMC4724586, DOI: 10.4240/wjgs.v8.i1.41.Peer-Reviewed Original ResearchAnal cancerRoutine screeningIntraepithelial neoplasiaCervical cancerAnal cancer preventionInvasive anal cancerSimilar tumor biologyAnal intraepithelial neoplasiaCancer screening recommendationsRisk stratification strategiesHuman papilloma virusAnorectal examPapanicolaou (Pap) testingScreening recommendationsPapilloma virusClinical rationalePrecursor lesionsCancer preventionScreening modalityPotential screening modalitiesEarly diagnosisLow prevalenceGeneral populationDisease processTumor biology
2015
Patient Symptomatology in Anal Dysplasia
Hicks CW, Wick EC, Leeds IL, Efron JE, Gearhart SL, Safar B, Fang SH. Patient Symptomatology in Anal Dysplasia. JAMA Surgery 2015, 150: 563-569. PMID: 25874644, DOI: 10.1001/jamasurg.2015.28.Peer-Reviewed Original ResearchConceptsLow-grade dysplasiaAnal dysplasiaHigh-grade dysplasiaAnal painAnal lesionsMultivariable analysisPatient symptomatologyHigh-grade anal dysplasiaHigh-risk patientsMajority of patientsPhysical examination findingsHigh-risk factorsAnal PapanicolaouInitial presentationExamination findingsHIV statusPatient's symptomsPhysical examinationMedical historyBiopsy specimensSilent diseaseRoutine screeningMAIN OUTCOMEHigh riskPatients