2020
CXC Chemokine/Receptor Axis Profile and Metastasis in Prostate Cancer
Nagaya N, Lee G, Horie S, Kim I. CXC Chemokine/Receptor Axis Profile and Metastasis in Prostate Cancer. Frontiers In Molecular Biosciences 2020, 7: 579874. PMID: 33195424, PMCID: PMC7593595, DOI: 10.3389/fmolb.2020.579874.Peer-Reviewed Original ResearchLymph node metastasisPrimary prostate cancerChemokines/receptorsMetastatic prostate cancerNode metastasisProstate cancerReceptor expressionMetastatic sitesChemokine/receptor axisMultivariate logistic regression analysisLog-rank test resultsLogistic regression analysisCancer Genome AtlasBone metastasesIndependent predictorsLymph nodesPostoperative recurrenceDistant metastasisCXCL10 expressionMRNA expression dataReceptor axisMetastasisTeam databaseLow expressionCancer progression
1998
ABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA
KUNDU S, KIM I, ZELNER D, JANULIS L, GOODWIN S, ENGEL J, LEE C. ABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA. Journal Of Urology 1998, 160: 1883-1888. PMID: 9783979, DOI: 10.1016/s0022-5347(01)62437-6.Peer-Reviewed Original ResearchConceptsTGF-beta1 productionRenca cellsTGF-beta sensitivityRenal carcinoma cell linesCarcinoma cell linesInhibitory effectEndogenous TGF-beta1 productionWild-type Renca cellsCell linesTGF-beta receptor expressionTbetaR-II mRNAAggressive growth patternGrowth factor beta type II receptorTGF-beta1 mRNATGF-beta insensitivityPlasminogen activator inhibitorTbetaR-I mRNAType II receptorAbsence of expressionReceptor expressionTbetaR-IIII receptorsActivator inhibitorAggressive growthThymidine incorporationABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA
KUNDU S, KIM I, ZELNER D, JANULIS L, GOODWIN S, ENGEL J, LEE C. ABSENCE OF EXPRESSION OF TRANSFORMING GROWTH FACTOR-beta TYPE II RECEPTOR IS ASSOCIATED WITH AN AGGRESSIVE GROWTH PATTERN IN A MURINE RENAL CARCINOMA CELL LINE, RENCA. Journal Of Urology 1998, 160: 1883-1888.. DOI: 10.1097/00005392-199811000-00077.Peer-Reviewed Original ResearchT beta RRenca cellsTGF-beta sensitivityRenal carcinoma cell linesCarcinoma cell linesBeta RInhibitory effectWild-type Renca cellsCell linesTGF-beta receptor expressionAggressive growth patternGrowth factor beta type II receptorTGF-beta insensitivityPlasminogen activator inhibitorType II receptorAbsence of expressionReceptor expressionII receptorsActivator inhibitorAggressive growthTumor cellsThymidine incorporationRT-PCRCancer cellsReceptors
1996
Expression and localization of transforming growth factor-beta receptors type I and type II in the rat ventral prostate during regression.
Kim I, Ahn H, Zelner D, Park L, Sensibar J, Lee C. Expression and localization of transforming growth factor-beta receptors type I and type II in the rat ventral prostate during regression. Endocrinology 1996, 10: 107-15. PMID: 8838150, DOI: 10.1210/mend.10.1.8838150.Peer-Reviewed Original ResearchConceptsReceptor messenger RNARat ventral prostateType II receptorII receptorsVentral prostateReceptor expressionDay 7Growth factor-beta receptor type IType III receptor expressionTGF betaTGF-beta receptor type IIType IType II receptor proteinType II receptor expressionMessenger RNAEffects of androgensTGF-beta signaling receptorsReceptor type IReceptor type IIStromal-epithelial interactionsType IIProstatic epithelial cellsGrowth factor beta receptorWestern blot analysisImmunohistochemical study