2018
Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma.
Abajian A, Murali N, Savic LJ, Laage-Gaupp FM, Nezami N, Duncan JS, Schlachter T, Lin M, Geschwind JF, Chapiro J. Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma. Journal Of Visualized Experiments 2018 PMID: 30371657, PMCID: PMC6235502, DOI: 10.3791/58382.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, HepatocellularHumansInjections, Intra-ArterialLiver NeoplasmsMachine LearningMaleMiddle AgedSurgery, Computer-AssistedConceptsIntra-arterial therapyN patientsHepatocellular carcinomaTrans-arterial therapiesIntra-arterial treatmentCohort of patientsStandard of careLikelihood of responseClinical research questionsSurgical resectionNew patientsTreatment responseUnivariate associationsPatientsTraining patientsInterventional radiologyTherapyCarcinomaTreatmentImage-guided therapyOutcomesFinal modelImaging dataResectionResponse
2012
Volumetric Intraoperative Brain Deformation Compensation: Model Development and Phantom Validation
DeLorenzo C, Papademetris X, Staib LH, Vives KP, Spencer DD, Duncan JS. Volumetric Intraoperative Brain Deformation Compensation: Model Development and Phantom Validation. IEEE Transactions On Medical Imaging 2012, 31: 1607-1619. PMID: 22562728, PMCID: PMC3600363, DOI: 10.1109/tmi.2012.2197407.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBiomechanical PhenomenaBrainGame TheoryHumansImaging, Three-DimensionalModels, NeurologicalPhantoms, ImagingReproducibility of ResultsSkullSurgery, Computer-AssistedConceptsLinear elastic modelSurface displacementsElastic modelBrain deformationVolumetric brain deformationMaterial parametersMaterial propertiesRealistic brain phantomDeformationBiomechanical modelIntraoperative brainModel accuracyLocalization errorPhantom validationAccurate surgical guidanceModel solutionsModel developmentInitial estimationDisplacementModel sensitivityQuantitative validationPhantom resultsPreoperative imagesSurgical guidancePreliminary application
2010
Image-Guided Intraoperative Cortical Deformation Recovery Using Game Theory: Application to Neocortical Epilepsy Surgery
DeLorenzo C, Papademetris X, Staib LH, Vives KP, Spencer DD, Duncan JS. Image-Guided Intraoperative Cortical Deformation Recovery Using Game Theory: Application to Neocortical Epilepsy Surgery. IEEE Transactions On Medical Imaging 2010, 29: 322-338. PMID: 20129844, PMCID: PMC2824434, DOI: 10.1109/tmi.2009.2027993.Peer-Reviewed Original ResearchConceptsDeformation estimationSurface deformationBrain surface deformationSurface deformation estimationPreoperative brain imagesCortical surface deformationSurface trackingCamera calibration parametersDisplacement errorStereo vision systemBrain deformationDeformationCalibration parametersBiomechanical modelIntraoperative brainCalibration errorsPhysical processesVision systemVivo casesCamera calibrationStereo systemInitial conditionsImage acquisitionErrorEstimation
2009
From medical image computing to computer‐aided intervention: development of a research interface for image‐guided navigation
Papademetris X, DeLorenzo C, Flossmann S, Neff M, Vives KP, Spencer DD, Staib LH, Duncan JS. From medical image computing to computer‐aided intervention: development of a research interface for image‐guided navigation. International Journal Of Medical Robotics And Computer Assisted Surgery 2009, 5: 147-157. PMID: 19301361, PMCID: PMC2796181, DOI: 10.1002/rcs.241.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsHumansImaging, Three-DimensionalNeurosurgical ProceduresRoboticsSoftwareSoftware DesignSurgery, Computer-AssistedConceptsResearch interfaceNavigation systemApplication programming interfaceDual computer systemComputer-aided interventionsSurgery navigation systemImage-guided navigation systemProgramming interfaceClient programNetwork interfacesMedical imagesImage-guided navigationResearch softwareReal timeViable solutionSoftwareImage analysis softwareTool positionVersatile linkAnalysis softwareImagesInterfaceNavigationSystemResearch techniques
2007
Challenges in image-guided therapy system design
DiMaio S, Kapur T, Cleary K, Aylward S, Kazanzides P, Vosburgh K, Ellis R, Duncan J, Farahani K, Lemke H, Peters T, Lorensen W, Gobbi D, Haller J, Clarke L, Pizer S, Taylor R, Galloway R, Fichtinger G, Hata N, Lawson K, Tempany C, Kikinis R, Jolesz F. Challenges in image-guided therapy system design. NeuroImage 2007, 37: s144-s151. PMID: 17644360, PMCID: PMC3780776, DOI: 10.1016/j.neuroimage.2007.04.026.Peer-Reviewed Original ResearchA Comprehensive System for Intraoperative 3D Brain Deformation Recovery
DeLorenzo C, Papademetris X, Vives KP, Spencer DD, Duncan JS. A Comprehensive System for Intraoperative 3D Brain Deformation Recovery. Lecture Notes In Computer Science 2007, 10: 553-561. PMID: 18044612, PMCID: PMC2864112, DOI: 10.1007/978-3-540-75759-7_67.Peer-Reviewed Original ResearchConceptsBrain deformationLinear elastic modelVolumetric brain deformationDeformation recoverySurface trackingSurface displacementsElastic modelRealistic brain phantomDeformationBiomechanical modelLarge brain deformationsIntraoperative brainFeature detectionSemiautomatic strategyBrain phantomPreoperative imagesDisplacement
2006
Nonrigid 3D Brain Registration Using Intensity/Feature Information
DeLorenzo C, Papademetris X, Wu K, Vives KP, Spencer D, Duncan JS. Nonrigid 3D Brain Registration Using Intensity/Feature Information. Lecture Notes In Computer Science 2006, 9: 932-939. PMID: 17354980, PMCID: PMC2864121, DOI: 10.1007/11866565_114.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsArtificial IntelligenceBayes TheoremBrainEpilepsyHumansImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingPattern Recognition, AutomatedReproducibility of ResultsSensitivity and SpecificitySubtraction TechniqueSurgery, Computer-AssistedConceptsStereo camera imagesCamera calibration errorsPreoperative brain imagesSurface tracking algorithmFeature informationCamera imagesTracking algorithmBrain imagesOptimization termSurface detectionRobust modelImagesBrain registrationIntraoperative brainCalibration errorsAlgorithmAccuracyRegistrationModelInformation