Impact of an In Situ Component on Outcome After In-Breast Tumor Recurrence in Patients Treated with Breast-Conserving Therapy
Laird J, Lok B, Siu C, Cahlon O, Khan A, McCormick B, Powell S, Cody H, Wen H, Ho A, Braunstein L. Impact of an In Situ Component on Outcome After In-Breast Tumor Recurrence in Patients Treated with Breast-Conserving Therapy. Annals Of Surgical Oncology 2017, 25: 154-163. PMID: 29094250, PMCID: PMC5827945, DOI: 10.1245/s10434-017-6209-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateMastectomy, SegmentalMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingNeoplasms, Second PrimaryProportional Hazards ModelsRadiotherapy, AdjuvantSurvival RateConceptsDisease-free survivalBreast-conserving therapyBreast tumor recurrenceTrue recurrenceNew primarySitu componentOverall survivalTumor sizeTumor recurrenceFive-year disease-free survivalTR groupCox proportional hazards regression modelLower disease-free survivalWorse disease-free survivalProportional hazards regression modelsSimultaneous distant metastasesKaplan-Meier methodHazards regression modelsLog-rank testAxillary surgeryDFS eventsNode involvementLymphovascular invasionMargin statusUnresectable recurrence