Challenges in HSV encephalitis: normocellular CSF, unremarkable CCT, and atypical MRI findings
Bewersdorf J, Koedel U, Patzig M, Dimitriadis K, Paerschke G, Pfister H, Klein M. Challenges in HSV encephalitis: normocellular CSF, unremarkable CCT, and atypical MRI findings. Infection 2018, 47: 267-273. PMID: 30506479, DOI: 10.1007/s15010-018-1257-7.Peer-Reviewed Original ResearchConceptsHSV encephalitisCerebrospinal fluidLevel of clinical suspicionCerebrospinal fluid cell countSpectrum of clinical presentationsMagnetic resonance imaging abnormalitiesSevere brainstem involvementTemporal lobe hemorrhageTreated with acyclovirFocal neurological deficitsLife-saving therapyAcyclovir therapyClinical suspicionBrainstem involvementAtypical presentationClinical presentationAtypical findingsDiagnostic challengeClinical featuresDelayed administrationLaboratory findingsClinical outcomesCT scanSimplex virusNeurological deficits