Leukapheresis for the management of hyperleukocytosis in acute myeloid leukemia—A systematic review and meta‐analysis
Bewersdorf JP, Giri S, Tallman MS, Zeidan AM, Stahl M. Leukapheresis for the management of hyperleukocytosis in acute myeloid leukemia—A systematic review and meta‐analysis. Transfusion 2020, 60: 2360-2369. PMID: 32776542, PMCID: PMC8631180, DOI: 10.1111/trf.15994.Peer-Reviewed Original ResearchConceptsAcute myeloid leukemiaEarly mortality rateWhite blood cellsRisk ratioMyeloid leukemiaMortality rateSystematic reviewShort-term mortality benefitHigh early mortality rateManagement of hyperleukocytosisCochrane Central RegisterIndividual study estimatesWeb of ScienceCentral RegisterMortality benefitControlled TrialsPrimary outcomeEarly mortalityRetrospective studyMultiarm studiesTreatment strategiesTwo-armEarly deathLeukapheresisPatients