2021
Molecules from the Microbiome
Shine EE, Crawford JM. Molecules from the Microbiome. Annual Review Of Biochemistry 2021, 90: 1-27. PMID: 33770448, DOI: 10.1146/annurev-biochem-080320-115307.Peer-Reviewed Original ResearchConceptsHuman microbiomeSpecific microbial moleculesSmall moleculesSecond genomeEcological nichesSpecies compositionGenetic capacityInteraction networksMicrobial moleculesMicrobiome editingBiochemical complexitySynthetic biologyMolecular mechanismsHuman cellsImmune system developmentChemical biologyFunctional interactionMicrobiomeDetailed mechanistic studiesBiologyHost responseMechanistic studiesGenomeMoleculesMicrobes
2010
Siderophores from Neighboring Organisms Promote the Growth of Uncultured Bacteria
D'Onofrio A, Crawford JM, Stewart EJ, Witt K, Gavrish E, Epstein S, Clardy J, Lewis K. Siderophores from Neighboring Organisms Promote the Growth of Uncultured Bacteria. Cell Chemical Biology 2010, 17: 254-264. PMID: 20338517, PMCID: PMC2895992, DOI: 10.1016/j.chembiol.2010.02.010.Peer-Reviewed Original ResearchConceptsCulturing of organismsUncultured isolatesUncultured bacteriaGrowth factorGrowth promotionCultured microbesCommunity establishmentBacterial speciesSediment biofilmHelper strainSiderophoresCultured organismsOrganismsLack of growthBacteriaPetri dishesSynthetic mediumSame environmentHabitatsIsolatesMicrobesSpeciesGrowthStrainsPromiscuity