2015
DOCK8-Deficient Mice Reveal a Crucial Role for Dendritic Cell Activity in the Initiation of the Allogeneic Response to Transfused Red Blood Cells
Eisenbarth S, Hendrickson J, Calabro S, Gallman A. DOCK8-Deficient Mice Reveal a Crucial Role for Dendritic Cell Activity in the Initiation of the Allogeneic Response to Transfused Red Blood Cells. Blood 2015, 126: 658. DOI: 10.1182/blood.v126.23.658.658.Peer-Reviewed Original ResearchAllogeneic red blood cellsDOCK8-deficient miceRed blood cellsT cellsDendritic cellsT cell activationAllogeneic responseB cellsImmune signalsCell activationT cell receptor transgenic miceSplenic dendritic cell subsetsBlood cellsDendritic cell activityInduction of alloimmunityDendritic cell subsetsHen egg lysozymeT cell primingDendritic cell migrationInnate immune cellsReceptor transgenic miceInnate immune signalsT cell zonesAntigen presenting cellsB cell responses
2008
Berkeley Mice with Sickle Cell Disease Are Not More Immunizable to Transfused HOD Red Blood Cells Than Sickle Trait Control Mice
HendricKson J, Archer D, Perry J, Hillyer C, Zimring J. Berkeley Mice with Sickle Cell Disease Are Not More Immunizable to Transfused HOD Red Blood Cells Than Sickle Trait Control Mice. Blood 2008, 112: 292. DOI: 10.1182/blood.v112.11.292.292.Peer-Reviewed Original ResearchCo-stimulatory molecule expressionSickle cell diseaseBerkeley miceAntigen presenting cellsCell diseaseSickle cell traitMolecule expressionForeign antigensRBC alloimmunizationBaseline inflammationDendritic cellsPresenting cellsRed blood cell alloimmunizationCell traitIndividual miceELISA 2 weeksRate of alloimmunizationRBC-specific expressionTransfusion of RBCsHuman blood group antigensLevel of illnessAntigen hen egg lysozymeDonor/recipientHigh rateTime of illness