Alloimmunization To HLA Class I Antigens But Not H-Y Antigens Is Associated With Transfusion In Children With Sickle Cell Disease
Nickel R, Hendrickson J, Kean L, Yee M, Bray R, Gebel H, Miklos D, Horan J. Alloimmunization To HLA Class I Antigens But Not H-Y Antigens Is Associated With Transfusion In Children With Sickle Cell Disease. Blood 2013, 122: 39. DOI: 10.1182/blood.v122.21.39.39.Peer-Reviewed Original ResearchHematopoietic stem cell transplantMinor histocompatibility antigensHuman leukocyte antigenSickle cell diseaseHLA class I antibodiesClass I human leukocyte antigenClass I antibodiesPediatric SCD patientsRBC transfusionHLA class IGraft rejectionSCD patientsY antigenHLA antibodiesChronic transfusionIgG antibodiesI antibodiesCell diseaseClass I HLA antibodiesHLA class II antibodiesClass II human leukocyte antigenRed blood cell transfusionManagement of SCDClass IHLA-identical transplantationAlterations In Specific Immune Cell Subsets In Children With Sickle Cell Disease
Nickel R, Hendrickson J, Horan J, Garrett A, Robertson J, Osunkwo I, Kean L. Alterations In Specific Immune Cell Subsets In Children With Sickle Cell Disease. Blood 2013, 122: 2208. DOI: 10.1182/blood.v122.21.2208.2208.Peer-Reviewed Original ResearchSickle cell diseaseWhite blood cellsTotal white blood cellsChronic transfusionImmune cell subsetsHU patientsImmune cell populationsSCD patientsT cellsCell subsetsHealthy controlsCell diseaseB cellsGraft rejectionNK cellsImmune systemBone marrow transplant rejectionT-cell subset analysisCell populationsRed blood cell alloimmunizationPediatric sickle cell diseaseSpecific immune cell subsetsDifferent immune cell populationsAbnormal immune activationB cell analysis