1998
Modulation of Circulating Cellular Adhesion Molecules in Postmenopausal Women With Coronary Artery Disease
Caulin-Glaser T, Farrell W, Pfau S, Zaret B, Bunger K, Setaro J, Brennan J, Bender J, Cleman M, Cabin H, Remetz M. Modulation of Circulating Cellular Adhesion Molecules in Postmenopausal Women With Coronary Artery Disease. Journal Of The American College Of Cardiology 1998, 31: 1555-1560. PMID: 9626834, DOI: 10.1016/s0735-1097(98)00145-4.Peer-Reviewed Original ResearchConceptsE2 replacement therapyCoronary artery diseaseVascular cell adhesion molecule-1Cellular adhesion moleculesPostmenopausal womenAdhesion molecule-1Premenopausal womenArtery diseaseCardioprotective effectsInflammatory responseAdhesion moleculesMolecule-1Incidence of CADControl groupInflammatory cytokine-induced expressionIntercellular adhesion molecule-1Expression of CAMsCell adhesion molecule-1Consecutive eligible subjectsAssociation of estrogenEndothelial cell activationCytokine-induced expressionFemale control groupSignificant increaseEnzyme-linked immunoabsorbant assay
1996
Effects of 17beta-estradiol on cytokine-induced endothelial cell adhesion molecule expression.
Caulin-Glaser T, Watson C, Pardi R, Bender J. Effects of 17beta-estradiol on cytokine-induced endothelial cell adhesion molecule expression. Journal Of Clinical Investigation 1996, 98: 36-42. PMID: 8690801, PMCID: PMC507398, DOI: 10.1172/jci118774.Peer-Reviewed Original ResearchConceptsCultured human umbilical vein ECEndothelial cell adhesion molecule expressionVascular cell adhesion molecule-1 inductionEstrogen receptor-mediated effectsCardiovascular protective roleCell adhesion molecule expressionAge-matched malesIncidence of atherosclerosisReceptor-mediated effectsAdhesion molecule expressionEndothelial cell activationHuman umbilical vein ECSimilar risk profilesSelectin mRNA levelsIL-1 activationPremenopausal womenAntagonist ICIMolecule expressionMononuclear leukocytesE-selectinChemotactic factorsCytokines resultsProtective roleCell activationLeukocyte adhesion