2023
Mechanical Thrombectomy for High-Risk Pulmonary Embolism: Insights From the US Cohort of the FLASH Registry
Horowitz J, Jaber W, Stegman B, Rosenberg M, Fanola C, Bhat A, Gondi S, Castle J, Ahmed M, Brown M, Amin R, Bisharat M, Butros P, DuCoffe A, Savin M, Pollak J, Weinberg M, Brancheau D, Toma C, Investigators F. Mechanical Thrombectomy for High-Risk Pulmonary Embolism: Insights From the US Cohort of the FLASH Registry. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 3: 101124. PMID: 39131977, PMCID: PMC11307390, DOI: 10.1016/j.jscai.2023.101124.Peer-Reviewed Original ResearchHigh-risk pulmonary embolismMajor adverse eventsPulmonary embolismMechanical thrombectomyAdverse eventsUS cohortProcedure-related adverse eventsAcute mortalityDepressed cardiac indexDevice-related mortalityRisk pulmonary embolismSubset of patientsSystolic blood pressureFurther prospective dataMin/m2Intensive care unitElevated lactate levelsComers registryFlowTriever SystemMajor bleedingCardiac indexCardiology guidelinesAcute outcomesBlood pressureCare unitAcute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism.
Toma C, Jaber W, Weinberg M, Bunte M, Khandhar S, Stegman B, Gondi S, Chambers J, Amin R, Leung D, Kado H, Brown M, Sarosi M, Bhat A, Castle J, Savin M, Siskin G, Rosenberg M, Fanola C, Horowitz J, Pollak J. Acute outcomes for the full US cohort of the FLASH mechanical thrombectomy registry in pulmonary embolism. EuroIntervention 2023, 18: 1201-1212. PMID: 36349702, PMCID: PMC9936254, DOI: 10.4244/eij-d-22-00732.Peer-Reviewed Original ResearchConceptsHigh-risk PEDevice-related deathsPulmonary artery pressureMajor adverse eventsAdverse eventsMechanical thrombectomyFlowTriever SystemArtery pressureUS cohortLarge real-world populationMean pulmonary artery pressureImmediate haemodynamic improvementIntraprocedural adverse eventsPrimary safety endpointRight ventricle/Favorable safety profileIntensive care unitPulmonary embolism treatmentReal-world populationDyspnoea improvementHaemodynamic improvementMajor bleedingRisk PECardiac indexCause mortality
2000
Liver Disease in Patients with Hereditary Hemorrhagic Telangiectasia
Garcia-Tsao G, Korzenik J, Young L, Henderson K, Jain D, Byrd B, Pollak J, White R. Liver Disease in Patients with Hereditary Hemorrhagic Telangiectasia. New England Journal Of Medicine 2000, 343: 931-936. PMID: 11006369, DOI: 10.1056/nejm200009283431305.Peer-Reviewed Original ResearchConceptsHereditary hemorrhagic telangiectasiaHigh-output heart failureHemorrhagic telangiectasiaHeart failureMedian periodPortal hypertensionLiver involvementClinical findingsBiliary diseasePulmonary capillary wedge pressureElevated alkaline phosphatase levelsHepatic sinusoidal pressureSymptomatic liver involvementTypical clinical presentationAlkaline phosphatase levelsAutosomal dominant disorderHyperdynamic circulationAngiodysplastic lesionsCardiac indexLiver transplantationVariceal bleedingWedge pressureMedical therapyRendu-OslerClinical presentation