A randomized comparison of indwelling pleural catheter and doxycycline pleurodesis in the management of malignant pleural effusions
Putnam J, Light R, Rodriguez R, Ponn R, Olak J, Pollak J, Lee R, Payne D, Graeber G, Kovitz K. A randomized comparison of indwelling pleural catheter and doxycycline pleurodesis in the management of malignant pleural effusions. Cancer 1999, 86: 1992-1999. PMID: 10570423, DOI: 10.1002/(sici)1097-0142(19991115)86:10<1992::aid-cncr16>3.0.co;2-m.Peer-Reviewed Original ResearchConceptsMalignant pleural effusionPleural catheterDoxycycline pleurodesisPleural effusionIndwelling catheterLate recurrenceTube thoracostomyRecurrent symptomatic malignant pleural effusionsSymptomatic malignant pleural effusionIndwelling pleural catheterMedian hospitalization timeManagement of patientsRelief of dyspneaTreatment of patientsMulti-institutional studyQuality of lifeCatheter groupSpontaneous pleurodesisDoxycycline groupSymptomatic improvementHospitalization timeRandomized comparisonShorter hospitalizationOutpatient basisSuccessful treatment