1999
A randomized comparison of indwelling pleural catheter and doxycycline pleurodesis in the management of malignant pleural effusions
Putnam J, Light R, Rodriguez R, Ponn R, Olak J, Pollak J, Lee R, Payne D, Graeber G, Kovitz K. A randomized comparison of indwelling pleural catheter and doxycycline pleurodesis in the management of malignant pleural effusions. Cancer 1999, 86: 1992-1999. PMID: 10570423, DOI: 10.1002/(sici)1097-0142(19991115)86:10<1992::aid-cncr16>3.0.co;2-m.Peer-Reviewed Original ResearchConceptsMalignant pleural effusionPleural catheterDoxycycline pleurodesisPleural effusionIndwelling catheterLate recurrenceTube thoracostomyRecurrent symptomatic malignant pleural effusionsSymptomatic malignant pleural effusionIndwelling pleural catheterMedian hospitalization timeManagement of patientsRelief of dyspneaTreatment of patientsMulti-institutional studyQuality of lifeCatheter groupSpontaneous pleurodesisDoxycycline groupSymptomatic improvementHospitalization timeRandomized comparisonShorter hospitalizationOutpatient basisSuccessful treatment
1994
Intrapleural Urokinase in the Treatment of Loculated Pleural Effusions
Pollak J, Passik C. Intrapleural Urokinase in the Treatment of Loculated Pleural Effusions. CHEST Journal 1994, 105: 868-873. PMID: 8131554, DOI: 10.1378/chest.105.3.868.Peer-Reviewed Original ResearchConceptsComplex pleural effusionsTube drainagePleural effusionPleural processesIntrapleural urokinase instillationLoculated pleural fluidComputed tomography scanLoculated pleural effusionIntrapleural urokinasePersistent fluidUK instillationUrokinase instillationAdequate trialClinical improvementIntrapleural instillationIntrapleural administrationTube thoracostomyDisease 6Complete resolutionSimple drainagePleural cavityPleural fluidTomography scanRadiographic demonstrationInstillation