Featured Publications
Infection by SARS‐CoV‐2 with alternate frequencies of mRNA vaccine boosting
Townsend J, Hassler H, Dornburg A. Infection by SARS‐CoV‐2 with alternate frequencies of mRNA vaccine boosting. Journal Of Medical Virology 2023, 95: e28461. PMID: 36602045, DOI: 10.1002/jmv.28461.Peer-Reviewed Original ResearchConceptsSARS-CoV-2Anti-spike IgG antibodiesWaning of antibodiesVaccine boostingBooster vaccinationBreakthrough infectionsAntibody levelsIgG antibodiesMRNA vaccinesProbability of infectionInfectionEndemic transmissionIndividual infectionsPredominant variantCOVID-19 pandemicMessenger RNAAntibodiesDisease spreadBNT162b2HospitalizationMorbidityVaccinationWidespread uptakeVaccineMortality
2022
Quarantine and serial testing for variants of SARS-CoV-2 with benefits of vaccination and boosting on consequent control of COVID-19
Wells CR, Pandey A, Gokcebel S, Krieger G, Donoghue AM, Singer BH, Moghadas SM, Galvani AP, Townsend JP. Quarantine and serial testing for variants of SARS-CoV-2 with benefits of vaccination and boosting on consequent control of COVID-19. PNAS Nexus 2022, 1: pgac100. PMID: 35909795, PMCID: PMC9335027, DOI: 10.1093/pnasnexus/pgac100.Peer-Reviewed Original ResearchSARS-CoV-2Serial testingSerial testing strategyHigh population immunityQuarantine durationBenefits of vaccinationSARS-CoV-2 variantsDisease time courseCOVID-19CoV-2 variantsPublic health toolVaccine boostingThird doseVaccination statusVaccination coveragePopulation immunityCoV-2Health toolsDisease control effortsInfected casesLocal transmissionInfectiousness profileVaccinationTime courseImmunity
2016
One Health approach to cost-effective rabies control in India
Fitzpatrick MC, Shah HA, Pandey A, Bilinski AM, Kakkar M, Clark AD, Townsend JP, Abbas SS, Galvani AP. One Health approach to cost-effective rabies control in India. Proceedings Of The National Academy Of Sciences Of The United States Of America 2016, 113: 14574-14581. PMID: 27994161, PMCID: PMC5187709, DOI: 10.1073/pnas.1604975113.Peer-Reviewed Original ResearchConceptsHuman rabiesRabies deathsCanine vaccinationStray dogsHuman rabies deathsRabies controlCost-effectiveness thresholdPostexposure vaccinationWHO criteriaDog bitesAutopsy dataHealth outcomesHealth approachSurveillance dataVaccinationCost-effective strategyDogsRabiesRabies surveillance dataOne-thirdCost-Effectiveness of Pertussis Vaccination During Pregnancy in the United States
Atkins KE, Fitzpatrick MC, Galvani AP, Townsend JP. Cost-Effectiveness of Pertussis Vaccination During Pregnancy in the United States. American Journal Of Epidemiology 2016, 183: 1159-1170. PMID: 27188951, PMCID: PMC4908210, DOI: 10.1093/aje/kwv347.Peer-Reviewed Original ResearchConceptsMaternal vaccinationAdult vaccinationWorld Health Organization criteriaPrimary vaccination seriesVaccination of mothersRecent epidemiologic evidenceAge-stratified transmission modelMaternal antibody transferPertussis vaccinationPostpartum vaccinationVaccination seriesAntibody transferEpidemiologic evidenceOrganization criteriaPertussis incidenceDisease burdenCurrent recommendationsSevere casesVaccinationInfantsPregnancyDirect protectionUS mothersMothersPertussis
2015
Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US
Alfaro-Murillo JA, Townsend JP, Galvani AP. Optimizing age of cytomegalovirus screening and vaccination to avert congenital disease in the US. Vaccine 2015, 34: 225-229. PMID: 26631416, DOI: 10.1016/j.vaccine.2015.11.039.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCytomegalovirus InfectionsCytomegalovirus VaccinesDisease Transmission, InfectiousFemaleHumansImmunization ScheduleInfantInfant, NewbornInfectious Disease Transmission, VerticalMaleMass ScreeningMiddle AgedUnited StatesYoung AdultConceptsVaccine waningVaccine efficacyOptimal ageCMV vaccine candidatesLongitudinal clinical evaluationChild-bearing yearsYears of ageTransmission dynamicsCMV prevalenceCMV vaccinationCytomegalovirus ScreeningSeronegative femalesCongenital infectionCytomegalovirus infectionVaccine protectionSuch vaccinationClinical evaluationClinical trialsHearing lossVaccine candidatesVaccinationDemographic dataCongenital diseaseCognitive deficitsIndirect protectionHarnessing Case Isolation and Ring Vaccination to Control Ebola
Wells C, Yamin D, Ndeffo-Mbah ML, Wenzel N, Gaffney SG, Townsend JP, Meyers LA, Fallah M, Nyenswah TG, Altice FL, Atkins KE, Galvani AP. Harnessing Case Isolation and Ring Vaccination to Control Ebola. PLOS Neglected Tropical Diseases 2015, 9: e0003794. PMID: 26024528, PMCID: PMC4449200, DOI: 10.1371/journal.pntd.0003794.Peer-Reviewed Original ResearchConceptsRing vaccinationCase isolationContact tracingLimited initial supplyPost-exposure protectionMass vaccination campaignNon-pharmaceutical control measuresPublic health agenciesCandidate vaccinesVaccination campaignVaccinationCase contactsEbola casesEbola transmissionHealth agenciesIncidence dataLow efficacyVaccineEbola outbreakEffective alternativeMore contactEbolaSierra LeoneBeneficial supplementControl measures
2012
Reevaluation of Epidemiological Data Demonstrates That It Is Consistent With Cross-Immunity Among Human Papillomavirus Types
Durham DP, Poolman EM, Ibuka Y, Townsend JP, Galvani AP. Reevaluation of Epidemiological Data Demonstrates That It Is Consistent With Cross-Immunity Among Human Papillomavirus Types. The Journal Of Infectious Diseases 2012, 206: 1291-1298. PMID: 22872732, PMCID: PMC3448971, DOI: 10.1093/infdis/jis494.Peer-Reviewed Original ResearchConceptsHuman papillomavirus typesEpidemiological dataHPV typesOdds ratioPapillomavirus typesType replacementSpecific HPV typesHPV types 16Future vaccine studiesHPV vaccinationHPV infectionVaccine studiesEpidemiological observationsType 16Single infectionType 18Multiple infectionsType 6Cross immunityVaccinationInfectionPrevalenceEpidemiological modelEpidemiological dynamicsHPVThe influence of altruism on influenza vaccination decisions
Shim E, Chapman GB, Townsend JP, Galvani AP. The influence of altruism on influenza vaccination decisions. Journal Of The Royal Society Interface 2012, 9: 2234-2243. PMID: 22496100, PMCID: PMC3405754, DOI: 10.1098/rsif.2012.0115.Peer-Reviewed Original ResearchConceptsInfluenza vaccination decisionsVaccination decisionsImpact of altruismInfluence of altruismVaccination policyGame theoryPersonal payoffAltruismInfluenza vaccinationOptimal vaccination policiesDisease burdenPublic health outcomesHealth outcomesAltruistic motivationTotal costPolicyDecisionsEpidemiological modelPotential strategyPayoffsAssumptionSurvey studyMorbidityVaccinationFundamental assumptions