2000
Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: Results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging
Federle M, Chezmar J, Rubin D, Weinreb J, Freeny P, Schmiedl U, Brown J, Borrello J, Lee J, Semelka R, Mattrey R, Dachman A, Saini S, Harms S, Mitchell D, Anderson M, Halford H, Bennett W, Young S, Rifkin M, Gay S, Ballerini R, Sherwin P, Robison R. Efficacy and safety of mangafodipir trisodium (MnDPDP) injection for hepatic MRI in adults: Results of the U.S. Multicenter phase III clinical trials. Efficacy of early imaging. Journal Of Magnetic Resonance Imaging 2000, 12: 689-701. PMID: 11050638, DOI: 10.1002/1522-2586(200011)12:5<689::aid-jmri5>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsUnenhanced magnetic resonance imagingMagnetic resonance imagingMangafodipir trisodium injectionFinal diagnosisMulticenter phase III clinical trialContrast-enhanced computed tomography examinationPhase III clinical trialsContrast-enhanced magnetic resonance imagingInjection of MnDPDPPatient's final diagnosisHepatic magnetic resonance imagingComputed tomography examinationEnhanced magnetic resonance imagingFocal liver diseaseAdditional diagnostic informationFocal liver lesionsLiver diseaseEarly imagingMRI evaluationHepatic massClinical trialsTomography examinationIntravenous administrationPatient managementRadiologic diagnosisSafety and Efficacy of Mangafodipir Trisodium (MnDPDP) Injection for Hepatic MRI in Adults: Results of the U.S. Multicenter Phase III Clinical Trials (Safety)
Federle M, Chezmar J, Rubin D, Weinreb J, Freeny P, Semelka R, Brown J, Borrello J, Lee J, Mattrey R, Dachman A, Saini S, Harmon B, Fenstermacher M, Pelsang R, Harms S, Mitchell D, Halford H, Anderson M, Johnson C, Francis I, Bova J, Kenney P, Klippenstein D, Foster G, Turner D, Stillman A, Nelson R, Young S, Patt R, Rifkin M, Seltzer S, Gay S, Robison R, Sherwin P, Ballerini R. Safety and Efficacy of Mangafodipir Trisodium (MnDPDP) Injection for Hepatic MRI in Adults: Results of the U.S. Multicenter Phase III Clinical Trials (Safety). Journal Of Magnetic Resonance Imaging 2000, 12: 186-197. PMID: 10931579, DOI: 10.1002/1522-2586(200007)12:1<186::aid-jmri21>3.0.co;2-2.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal PainAdultAgedAged, 80 and overCardiovascular DiseasesContrast MediaDiagnosis, DifferentialEdetic AcidFemaleHumansImage EnhancementInjections, IntravenousLiver CirrhosisLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedPainPregnancyPyridoxal PhosphateRisk AssessmentSensitivity and SpecificityVomitingConceptsMagnetic resonance imagingMangafodipir trisodium injectionAdverse eventsMulticenter phase III clinical trialContrast-enhanced computed tomography examinationPhase III clinical trialsUnenhanced magnetic resonance imagingInjection of MnDPDPInjection-associated discomfortSerious adverse eventsShort-term safetyHepatic magnetic resonance imagingComputed tomography examinationSignificant short-term riskShort-term riskFocal liver lesionsClinical trialsTomography examinationLaboratory valuesLiver lesionsResonance imagingVital signsPatientsMnDPDPInjectionHepatic MR Imaging with a Dynamic Contrast-enhanced Isotropic Volumetric Interpolated Breath-hold Examination: Feasibility, Reproducibility, and Technical Quality
Lee V, Lavelle M, Rofsky N, Laub G, Thomasson D, Krinsky G, Weinreb J. Hepatic MR Imaging with a Dynamic Contrast-enhanced Isotropic Volumetric Interpolated Breath-hold Examination: Feasibility, Reproducibility, and Technical Quality. Radiology 2000, 215: 365-72. PMID: 10796909, DOI: 10.1148/radiology.215.2.r00ma16365.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAdultAgedAged, 80 and overCohort StudiesContrast MediaFeasibility StudiesFemaleFollow-Up StudiesGadolinium DTPAHepatic ArteryHepatic VeinsHumansImage EnhancementImage Processing, Computer-AssistedLiverLiver DiseasesMagnetic Resonance ImagingMaleMiddle AgedPortal VeinQuality ControlReproducibility of ResultsRespirationVena Cava, InferiorConceptsContrast materialMagnetic resonance imaging examinationsPatient underwent repeatVascular anatomic variantsDynamic contrastPortal venous phaseArterial dominanceUnderwent repeatVenous anatomyAnatomic variantsImaging examinationsTest bolusTest doseVenous phaseArterial phaseRepeat studyHepatic MRGadopentetate dimeglumineGradient-echo imagingTechnical qualityEnhanced acquisitionMaximal enhancementBreath-hold imagesOriginal studyAngiotensin-converting enzyme inhibitor-enhanced phase-contrast MR imaging to measure renal artery velocity waveforms in patients with suspected renovascular hypertension.
Lee V, Rofsky N, Ton A, Johnson G, Krinsky G, Weinreb J. Angiotensin-converting enzyme inhibitor-enhanced phase-contrast MR imaging to measure renal artery velocity waveforms in patients with suspected renovascular hypertension. American Journal Of Roentgenology 2000, 174: 499-508. PMID: 10658731, DOI: 10.2214/ajr.174.2.1740499.Peer-Reviewed Original Research
1999
Three-dimensional Gadolinium-enhanced MR Venographic Evaluation of Patency of Central Veins in the Thorax: Initial Experience
Shinde T, Lee V, Rofsky N, Krinsky G, Weinreb J. Three-dimensional Gadolinium-enhanced MR Venographic Evaluation of Patency of Central Veins in the Thorax: Initial Experience. Radiology 1999, 213: 555-60. PMID: 10551241, DOI: 10.1148/radiology.213.2.r99nv27555.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overFemaleGadoliniumHumansMagnetic Resonance AngiographyMaleMiddle AgedPhlebographyRetrospective StudiesThoraxConceptsVenographic findingsCentral veinMR venographyCatheter placementConventional venographyCentral venous catheter placementArteriovenous hemodialysis graftsHemodialysis catheter placementThoracic central veinsVenous access sitesMagnetic resonance venographyVenous access devicesVenous catheter placementMultiplanar reconstruction imagesVenographic evaluationFourth patientHemodialysis graftsRetrospective studyMedical recordsAccess siteIntravenous administrationThree-dimensional GadoliniumVenographyPatientsContrast material
1998
The effects of apnea on timing examinations for optimization of gadolinium-enhanced MRA of the thoracic aorta and arch vessels.
Krinsky G, Kaminer E, Lee V, Rofsky N, Weinreb J. The effects of apnea on timing examinations for optimization of gadolinium-enhanced MRA of the thoracic aorta and arch vessels. Journal Of Computer Assisted Tomography 1998, 22: 677-81. PMID: 9754096, DOI: 10.1097/00004728-199809000-00001.Peer-Reviewed Original ResearchConceptsEffects of apneaThoracic aortaGadolinium-enhanced 3D MR angiographyMR angiographyFree breathingArch vesselsTiming examinationGadolinium-enhanced MR angiographyProximal neckIndividual patientsArterial enhancementApneaBranch vesselsGadolinium contrast agentCirculation timePatientsVenous enhancementRespiratory patternLow dosesBreathingAortaAxial imagesMR angiogramsSignificant differencesExamination
1997
Peripheral vascular disease evaluated with reduced-dose gadolinium-enhanced MR angiography.
Rofsky N, Johnson G, Adelman M, Rosen R, Krinsky G, Weinreb J. Peripheral vascular disease evaluated with reduced-dose gadolinium-enhanced MR angiography. Radiology 1997, 205: 163-9. PMID: 9314979, DOI: 10.1148/radiology.205.1.9314979.Peer-Reviewed Original ResearchConceptsPeripheral vascular diseaseGadolinium-enhanced MR angiographyDigital subtraction angiographyVascular diseaseMR angiographyGadopentetate dimeglumineLower extremity peripheral vascular diseasePeripheral vascular areasExtent of diseaseMR angiography findingsGadolinium-enhanced magnetic resonance angiographyMagnetic resonance angiographyConventional digital subtraction angiographyStandard of referenceAngiography findingsMost patientsLess stenosisTreatment optionsLower extremitiesDSA findingsVascular areaAngiographyAnatomic segmentsAnatomic areasContrast materialGadolinium-enhanced body MR venography with subtraction technique.
Lebowitz J, Rofsky N, Krinsky G, Weinreb J. Gadolinium-enhanced body MR venography with subtraction technique. American Journal Of Roentgenology 1997, 169: 755-8. PMID: 9275892, DOI: 10.2214/ajr.169.3.9275892.Peer-Reviewed Original ResearchFatty and fibroglandular tissue volumes in the breasts of women 20-83 years old: comparison of X-ray mammography and computer-assisted MR imaging.
Lee N, Rusinek H, Weinreb J, Chandra R, Toth H, Singer C, Newstead G. Fatty and fibroglandular tissue volumes in the breasts of women 20-83 years old: comparison of X-ray mammography and computer-assisted MR imaging. American Journal Of Roentgenology 1997, 168: 501-6. PMID: 9016235, DOI: 10.2214/ajr.168.2.9016235.Peer-Reviewed Original ResearchTortuosity of the descending thoracic aorta simulating dissection on transesophageal echocardiography
Katz E, Applebaum R, Earls J, Krinsky G, Weinreb J, Kronzon I. Tortuosity of the descending thoracic aorta simulating dissection on transesophageal echocardiography. Journal Of The American Society Of Echocardiography 1997, 10: 83-87. PMID: 9046498, DOI: 10.1016/s0894-7317(97)80037-5.Peer-Reviewed Original ResearchSuppression of venous signal in time-of-flight MR angiography of the lower extremities after administration of gadopentetate dimeglumine.
Rofsky N, Purdy D, Johnson G, DeCorato D, Earls J, Krinsky G, Weinreb J. Suppression of venous signal in time-of-flight MR angiography of the lower extremities after administration of gadopentetate dimeglumine. Radiology 1997, 202: 177-82. PMID: 8988209, DOI: 10.1148/radiology.202.1.8988209.Peer-Reviewed Original ResearchConceptsGadopentetate dimeglumineLower extremitiesMR angiographyPeripheral vascular diseaseVenous signalDistal lower extremityMR angiogramsGadopentetate dimeglumine administrationStudent's t-testFlight MR angiographyAdult patientsAngiography timeVascular diseaseFlight MR angiogramsGradient echo sequenceAdministrationDimegluminePatientsAngiographyT-testAngiogramsExtremitiesMuscle tissueVenous suppressionImaging sectionsThoracic aorta: comparison of gadolinium-enhanced three-dimensional MR angiography with conventional MR imaging.
Krinsky G, Rofsky N, DeCorato D, Weinreb J, Earls J, Flyer M, Galloway A, Colvin S. Thoracic aorta: comparison of gadolinium-enhanced three-dimensional MR angiography with conventional MR imaging. Radiology 1997, 202: 183-93. PMID: 8988210, DOI: 10.1148/radiology.202.1.8988210.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAorta, ThoracicAortic Aneurysm, ThoracicAortic CoarctationAortic DiseasesAortic DissectionContrast MediaDrug CombinationsFemaleGadoliniumGadolinium DTPAHumansImage Processing, Computer-AssistedInfant, NewbornMagnetic Resonance AngiographyMagnetic Resonance ImagingMaleMeglumineMiddle AgedOrganometallic CompoundsPentetic AcidRetrospective StudiesConceptsThoracic aortic diseaseThree-dimensional MR angiographyConventional MR imagingMR angiographyIntramural hematomaAortic dissectionAortic diseaseVessel diseaseMR imagingFindings of surgeryChronic aortic dissectionThoracic MR imagingComparison of gadoliniumMagnetic resonance angiographyThree-dimensional magnetic resonance angiographyDiagnosis of aneurysmConsecutive patientsAngiographyResonance angiographyMR examinationsGadopentetate dimeglumineReader B.DiseaseGradient echo sequenceConventional MRHepatic arterial-phase dynamic gadolinium-enhanced MR imaging: optimization with a test examination and a power injector.
Earls J, Rofsky N, DeCorato D, Krinsky G, Weinreb J. Hepatic arterial-phase dynamic gadolinium-enhanced MR imaging: optimization with a test examination and a power injector. Radiology 1997, 202: 268-73. PMID: 8988222, DOI: 10.1148/radiology.202.1.8988222.Peer-Reviewed Original Research
1996
Breath-hold single-dose gadolinium-enhanced three-dimensional MR aortography: usefulness of a timing examination and MR power injector.
Earls J, Rofsky N, DeCorato D, Krinsky G, Weinreb J. Breath-hold single-dose gadolinium-enhanced three-dimensional MR aortography: usefulness of a timing examination and MR power injector. Radiology 1996, 201: 705-10. PMID: 8939219, DOI: 10.1148/radiology.201.3.8939219.Peer-Reviewed Original ResearchImage subtraction in gadolinium-enhanced MR imaging.
Lee V, Flyer M, Weinreb J, Krinsky G, Rofsky N. Image subtraction in gadolinium-enhanced MR imaging. American Journal Of Roentgenology 1996, 167: 1427-32. PMID: 8956572, DOI: 10.2214/ajr.167.6.8956572.Peer-Reviewed Original ResearchAsymmetric signal intensity of the renal collecting systems as a sign of unilateral renal artery stenosis following administration of gadopentetate dimeglumine.
Walsh P, Rofsky N, Krinsky G, Weinreb J. Asymmetric signal intensity of the renal collecting systems as a sign of unilateral renal artery stenosis following administration of gadopentetate dimeglumine. Journal Of Computer Assisted Tomography 1996, 20: 812-4. PMID: 8797919, DOI: 10.1097/00004728-199609000-00025.Peer-Reviewed Original Research
1995
Gadoteridol-enhanced MR imaging of malignant hepatic tumors: effects of triple versus standard doses on lesion-liver contrast.
Petersein J, Saini S, Mitchell D, Davis P, Johnson C, Kuhlman J, Parisky Y, Runge V, Weinreb J, Bernardino M. Gadoteridol-enhanced MR imaging of malignant hepatic tumors: effects of triple versus standard doses on lesion-liver contrast. American Journal Of Roentgenology 1995, 165: 1157-61. PMID: 7572495, DOI: 10.2214/ajr.165.5.7572495.Peer-Reviewed Original ResearchConceptsLesion-liver CNRLesion-liver contrastStandard doseHepatic lesionsMR imagingMalignant hepatic tumorsMalignant liver lesionsMalignant hepatic massesAdministration of gadoteridolMalignant hepatic lesionsT1-weighted spin-echo imagingLiver MR imagingStandard dosesHepatic massHepatic tumorsTriple doseHigh doseMalignant lesionsLiver lesionsLesionsLiver SNRDoseTime pointsGradient-echo imagingLiver signalT2‐weighted MR imaging of the chest: Comparison of electrocardiograph‐triggered conventional and turbo spin‐echo and nontriggered turbo spin‐echo sequences
Haddad J, Rofsky N, Ambrosino M, Naidich D, Weinreb J. T2‐weighted MR imaging of the chest: Comparison of electrocardiograph‐triggered conventional and turbo spin‐echo and nontriggered turbo spin‐echo sequences. Journal Of Magnetic Resonance Imaging 1995, 5: 325-329. PMID: 7633110, DOI: 10.1002/jmri.1880050317.Peer-Reviewed Original Research
1994
Comparison of contrast enhanced CT and Mn-DPDP enhanced MRI for detection of focal hepatic lesions initial findings
Birnbaum B, Weinreb J, Fernandez M, Brown J, Rofsky N, Young S. Comparison of contrast enhanced CT and Mn-DPDP enhanced MRI for detection of focal hepatic lesions initial findings. Clinical Imaging 1994, 18: 21-27. PMID: 8180855, DOI: 10.1016/0899-7071(94)90141-4.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingMn-DPDPMore lesionsRetrospective multi-institutional studyExtensive metastatic diseaseHepatic magnetic resonance imagingMulti-institutional studyFocal hepatic diseaseFocal liver lesionsN'-dipyridoxylethylenediamineMetastatic diseaseIntravenous bolusDose groupFatty liverHepatic diseaseComparison of ContrastHepatic lesionsComputed tomographyLiver lesionsCT studiesPatientsMumol/Resonance imagingBolus contrastLesions
1993
Hepatocellular tumors: characterization with Mn-DPDP-enhanced MR imaging.
Rofsky N, Weinreb J, Bernardino M, Young S, Lee J, Noz M. Hepatocellular tumors: characterization with Mn-DPDP-enhanced MR imaging. Radiology 1993, 188: 53-9. PMID: 8390072, DOI: 10.1148/radiology.188.1.8390072.Peer-Reviewed Original Research