2023
Expert consensus‐based guidance on approaches to opioid management in individuals with advanced cancer‐related pain and nonmedical stimulant use
Jones K, Khodyakov D, Han B, Arnold R, Dao E, Morrison J, Kapo J, Meier D, Paice J, Liebschutz J, Ritchie C, Merlin J, Bulls H. Expert consensus‐based guidance on approaches to opioid management in individuals with advanced cancer‐related pain and nonmedical stimulant use. Cancer 2023, 129: 3978-3986. PMID: 37691479, PMCID: PMC10910244, DOI: 10.1002/cncr.34921.Peer-Reviewed Original ResearchConceptsCancer-related painConsensus-based guidanceStimulant useUncertain appropriatenessOpioid taperingLonger prognosisShort prognosisPalliative careAddiction expertsNonmedical stimulant useRAND/UCLAStimulant use disorderHarm reduction measuresAdvanced cancerPatient prognosisClinical appropriatenessPainUse disordersPrognosisPatientsExpert consensusOpioidsCancerDelphi panelClinicians
2022
Consensus-Based Guidance on Opioid Management in Individuals With Advanced Cancer-Related Pain and Opioid Misuse or Use Disorder
Jones K, Khodyakov D, Arnold R, Bulls H, Dao E, Kapo J, Meier D, Paice J, Liebschutz J, Ritchie C, Merlin J. Consensus-Based Guidance on Opioid Management in Individuals With Advanced Cancer-Related Pain and Opioid Misuse or Use Disorder. JAMA Oncology 2022, 8: 1107-1114. PMID: 35771550, PMCID: PMC9247858, DOI: 10.1001/jamaoncol.2022.2191.Peer-Reviewed Original ResearchConceptsOpioid use disorderCancer-related painOpioid misuseUse disordersClinical scenariosUntreated opioid use disorderAddiction medicine specialistsCommon clinical scenariosDelphi panelImportant comorbidityAdvanced cancerPalliative careMAIN OUTCOMEMedicine specialistsAddiction specialistsPatientsLack of consensusPainAddiction cliniciansDisordersQualitative studyParticipantsComorbiditiesMisusePrognosisExpert Consensus-Based Guidance on Approaches to Opioid Management in Individuals with Advanced Cancer-Related Pain and Opioid Misuse or Use Disorder: Results of a Delphi Study (RP305)
Jones K, Merlin J, Arnold R, Meier D, Kapo J, Paice J. Expert Consensus-Based Guidance on Approaches to Opioid Management in Individuals with Advanced Cancer-Related Pain and Opioid Misuse or Use Disorder: Results of a Delphi Study (RP305). Journal Of Pain And Symptom Management 2022, 63: 1070. DOI: 10.1016/j.jpainsymman.2022.04.021.Peer-Reviewed Original ResearchOpioid use disorderBuprenorphine/naloxoneCancer-related painUrine drug testsOpioid misuseUncertain appropriatenessOpioid managementLonger prognosisComorbid painShort prognosisTraditional opioidsUse disordersUntreated opioid use disorderFull opioid agonistsPrescription of methadoneCancer pain managementDrug testsExpert panel consensusHigh-risk behaviorsMethadone accessTaper opioidsPrescribed opioidsUncontrolled painOUD treatmentPain managementExpert Panel Consensus on Management of Advanced Cancer-related Pain in Individuals with Opioid Use Disorder
Merlin J, Khodyakov D, Arnold R, Bulls H, Dao E, Kapo J, King C, Meier D, Paice J, Ritchie C, Liebschutz J. Expert Panel Consensus on Management of Advanced Cancer-related Pain in Individuals with Opioid Use Disorder. Journal Of Pain 2022, 23: 60. DOI: 10.1016/j.jpain.2022.03.226.Peer-Reviewed Original ResearchBuprenorphine/naloxoneFull agonist opioidsUncertain appropriatenessAdvanced cancerPalliative careCancer pain management strategiesCancer-related painAdvanced cancer painPain management strategiesOpioid use disorderExpert panel consensusConsensus-based guidanceCancer painDay dosingBuprenorphine/Optimal dosingMethadone clinicsUse disordersPatientsNaloxonePanel consensusPrognosisMethadoneHealth FoundationPain
2021
Expert Panel Consensus on Management of Advanced Cancer–Related Pain in Individuals With Opioid Use Disorder
Merlin JS, Khodyakov D, Arnold R, Bulls HW, Dao E, Kapo J, King C, Meier D, Paice J, Ritchie C, Liebschutz JM. Expert Panel Consensus on Management of Advanced Cancer–Related Pain in Individuals With Opioid Use Disorder. JAMA Network Open 2021, 4: e2139968. PMID: 34962565, DOI: 10.1001/jamanetworkopen.2021.39968.Peer-Reviewed Original ResearchConceptsOpioid use disorderFull agonist opioidsAdvanced cancerUncertain appropriatenessCancer painPalliative careUse disordersCancer pain managementAppropriateness of managementExpert panel consensusConsensus-based guidanceImportant comorbidityOpioid medicationsPain managementMethadone clinicsPainPatientsPanel consensusPrognosisCancerMethadoneDelphi processExpert panelMonthsOpioidsConsensus-based approach to managing opioids, including opioid misuse and opioid use disorder, in patients with serious illness: protocol for a modified Delphi process
King C, Arnold R, Dao E, Kapo J, Liebschutz J, Meier D, Paice J, Ritchie C, Czajkowski K, Khodyakov D, Merlin J. Consensus-based approach to managing opioids, including opioid misuse and opioid use disorder, in patients with serious illness: protocol for a modified Delphi process. BMJ Open 2021, 11: e045402. PMID: 34011593, PMCID: PMC8137210, DOI: 10.1136/bmjopen-2020-045402.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid misuseSerious illnessInstitutional review boardUse disordersBenefits of opioidsOpioid-related harmsPalliative care cliniciansInstitutional Research BoardPittsburgh Institutional Review BoardOpioid therapyPain managementCare cliniciansPalliative careClinical guidanceEthical approvalIllnessReview boardCliniciansDelphi processPatient casesImplementation toolkitRound 1OpioidsFinal consensus