An Unexpected Spectrum of p53 Mutations from Squamous Cell Carcinomas in Psoriasis Patients Treated with PUVA
Wang X, McNiff J, Klump V, Asgari M, Gasparro F. An Unexpected Spectrum of p53 Mutations from Squamous Cell Carcinomas in Psoriasis Patients Treated with PUVA. Photochemistry And Photobiology 1997, 66: 294-299. PMID: 9277151, DOI: 10.1111/j.1751-1097.1997.tb08658.x.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaCell carcinomaP53 mutationsTreatment of psoriasisType mutationsP53 tumor suppressor genePUVA patientsPsoriasis patientsUVB phototherapyImmune suppressionTherapeutic historyNormal controlsPatientsTumor progressionUVB exposureTumor suppressor geneCarcinomaSingle-strand conformational polymorphismLong-wavelength ultraviolet radiationHuman cancersPUVAPsoriasisSkin cellsPhotochemotherapyDipyrimidine sites