2023
IRF8 may be a useful marker for blastic plasmacytoid dendritic cell neoplasm, especially with weak CD123 expression
Tang H, Panse G, Braddock D, Perincheri S, Xu M, McNiff J. IRF8 may be a useful marker for blastic plasmacytoid dendritic cell neoplasm, especially with weak CD123 expression. Journal Of Cutaneous Pathology 2023, 50: 595-600. PMID: 37082914, DOI: 10.1111/cup.14439.Peer-Reviewed Original ResearchConceptsBlastic plasmacytoid dendritic cell neoplasmPlasmacytoid dendritic cell neoplasmDendritic cell neoplasmPunch biopsy specimenBiopsy specimenCell neoplasmsCase of BPDCNUseful markerTumor cellsTCL-1 expressionAtypical mononuclear cellsBone marrow involvementDiffuse dermal infiltrateDendritic cell lineagePotential diagnostic pitfallRegulatory factor 8TCL-1BPDCN casesCD123 expressionMarrow involvementDermal infiltrateCutaneous nodulesMyelodysplastic syndromeSkin nodulesMononuclear cells
1997
Pig but not human interferon-γ initiates human cell-mediated rejection of pig tissue in vivo
Sultan P, Murray A, McNiff J, Lorber M, Askenase P, Bothwell A, Pober J. Pig but not human interferon-γ initiates human cell-mediated rejection of pig tissue in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 8767-8772. PMID: 9238052, PMCID: PMC23121, DOI: 10.1073/pnas.94.16.8767.Peer-Reviewed Original ResearchConceptsHuman peripheral blood mononuclear cellsPeripheral blood mononuclear cellsPig skin graftsCell-mediated rejectionBlood mononuclear cellsIFN-gammaMononuclear cellsSkin graftsDermal microvesselsMajor histocompatibility complex (MHC) molecule expressionT cell-mediated rejectionPerivascular mononuclear cell infiltratesClass II major histocompatibility complex moleculesMononuclear cell infiltrateMajor histocompatibility complex moleculesTumor necrosis factorEvidence of injuryHistocompatibility complex moleculesPig endothelial cellsCell infiltrateIntradermal injectionMolecule expressionSparse infiltrateIntraperitoneal inoculationMouse microvessels