2021
Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis
Wang A, Fogel AL, Murphy MJ, Panse G, McGeary MK, McNiff JM, Bosenberg M, Vesely MD, Cohen JM, Ko CJ, King BA, Damsky W. Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis. JID Innovations 2021, 1: 100021. PMID: 34909719, PMCID: PMC8659380, DOI: 10.1016/j.xjidi.2021.100021.Peer-Reviewed Original ResearchAtopic dermatitisAtopic dermatitis casesInflammatory skin diseaseInflammatory skin disorderSubset of casesSitu hybridizationCytokine RNARoutine biopsyCytokine expressionPredominant cytokinePsoriasis casesCytokine targetsTreatment selectionDermatitis casesSkin disordersPsoriasis biomarkersSkin diseasesIndividual cytokinesIndividualized evaluationPsoriasisBiopsyBulk RNA sequencingCytokinesMolecular phenotypingPatients
1998
Psoralen photochemotherapy, clinical efficacy, and photomutagenicity: The role of molecular epidemiology in minimizing risks
Gasparro FP, Liao B, Foley PJ, Wang XM, McNiff J. Psoralen photochemotherapy, clinical efficacy, and photomutagenicity: The role of molecular epidemiology in minimizing risks. Environmental And Molecular Mutagenesis 1998, 31: 105-112. PMID: 9544188, DOI: 10.1002/(sici)1098-2280(1998)31:2<105::aid-em2>3.0.co;2-l.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaHuman squamous cell carcinomaP53 mutation spectrumMurine squamous cell carcinomaEfficacy of PUVATreatment of psoriasisP53 tumor suppressor geneMutation spectrumPsoriasis patientsUVB phototherapyClinical efficacyPsoralen photochemotherapyCell carcinomaTherapeutic historyPUVATumor progressionUVB exposureMolecular epidemiologyPatientsTumor suppressor geneHuman cancersCommon mutationsPsoriasisSkin cellsPhotochemotherapy
1997
An Unexpected Spectrum of p53 Mutations from Squamous Cell Carcinomas in Psoriasis Patients Treated with PUVA
Wang X, McNiff J, Klump V, Asgari M, Gasparro F. An Unexpected Spectrum of p53 Mutations from Squamous Cell Carcinomas in Psoriasis Patients Treated with PUVA. Photochemistry And Photobiology 1997, 66: 294-299. PMID: 9277151, DOI: 10.1111/j.1751-1097.1997.tb08658.x.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaCell carcinomaP53 mutationsTreatment of psoriasisType mutationsP53 tumor suppressor genePUVA patientsPsoriasis patientsUVB phototherapyImmune suppressionTherapeutic historyNormal controlsPatientsTumor progressionUVB exposureTumor suppressor geneCarcinomaSingle-strand conformational polymorphismLong-wavelength ultraviolet radiationHuman cancersPUVAPsoriasisSkin cellsPhotochemotherapyDipyrimidine sites