2024
Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma
Tang H, Laskin W, Luan Y, McNiff J, Zhan H. Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma. Journal Of Cutaneous Pathology 2024, 51: 604-608. PMID: 38711196, DOI: 10.1111/cup.14639.Peer-Reviewed Original ResearchEncapsulated papillary carcinomaDuctal carcinoma in situAnogenital mammary-like glandsMammary-like glandsInvasive carcinomaPapillary carcinomaBreast lesionsHidradenoma papilliferumLack of myoepithelial cellsInvasive mucinous carcinomaCutaneous adnexal tumorsCarcinoma in situInvasive ductal carcinomaGland typeVulvar tumorsAdnexal tumorsMucinous carcinomaDuctal carcinomaBreast carcinomaInvasive componentPapillary proliferationHistopathological featuresRare caseSkin tumorsCystic spaces
1999
A common human skin tumour is caused by activating mutations in β-catenin
Chan E, Gat U, McNiff J, Fuchs E. A common human skin tumour is caused by activating mutations in β-catenin. Nature Genetics 1999, 21: 410-413. PMID: 10192393, DOI: 10.1038/7747.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBeta CateninCytoskeletal ProteinsDeoxyribonucleases, Type II Site-SpecificDNA-Binding ProteinsGene FrequencyHair DiseasesHumansLymphoid Enhancer-Binding Factor 1Molecular Sequence DataMutationPilomatrixomaPolymerase Chain ReactionSequence Analysis, DNASkin NeoplasmsTrans-ActivatorsTranscription FactorsConceptsAdenomatous polyposis coliΒ-cateninLEF/TCFHair matrix cellsΒ-catenin/TCFHair follicle morphogenesisAmino-terminal segmentDownstream transcriptional activationMost colon cancersHuman skin tumorsActivated β-cateninTranscriptional activationCytoplasmic β-cateninTarget genesLEF-1Constitutive activationMatrix cellsWnt pathwayHuman pilomatricomasC-MycSkin tumorsCell tumorigenesisMutationsPolyposis coliBiochemical evidence