A New TCR Transgenic Model of GVHD Reveals That, Independent of Repertoire, Effector Memory T Cells Are Severely Limited, and Central Memory T Cells Somewhat Limited, in Their Ability to Cause GVHD.
Wilkinson K, Anderson B, McNiff J, Demetris A, Shlomchik W, Shlomchik M. A New TCR Transgenic Model of GVHD Reveals That, Independent of Repertoire, Effector Memory T Cells Are Severely Limited, and Central Memory T Cells Somewhat Limited, in Their Ability to Cause GVHD. Blood 2009, 114: 233. DOI: 10.1182/blood.v114.22.233.233.Peer-Reviewed Original ResearchEM T cellsCD4 T cellsCM CD4 T cellsCM T cellsDays post transplantMemory T cellsTCR transgenic modelT cellsPost transplantTs1 cellsLymph nodesCell recipientsWeight lossTransgenic modelCentral memory CD4 T cellsEffector memory T cellsAllogeneic stem cell transplantationMemory CD4 T cellsT cell receptor repertoireCentral memory TContext of GVHDInduction of GVHDInitiation of GVHDModel of GVHDRAG-deficient background