Humanized In Vivo Model for Streptococcal Impetigo
Scaramuzzino D, McNiff J, Bessen D. Humanized In Vivo Model for Streptococcal Impetigo. Infection And Immunity 2000, 68: 2880-2887. PMID: 10768985, PMCID: PMC97500, DOI: 10.1128/iai.68.5.2880-2887.2000.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDisease Models, AnimalFemaleHumansImpetigoMiceMice, SCIDSkinStreptococcal InfectionsStreptococcus pyogenesVirulenceConceptsStreptococcal impetigoVivo modelPattern AGross pathology scoresD strainsHuman neonatal foreskinEmm pattern ASevere infectionsEpidemiological findingsPathology scoresPurulent exudateSCID micePolymorphonuclear leukocytesPositive cocciNeonatal foreskinImpetigoC strainDays postinoculationMouse originVirulent strainGranular keratinocytesIntact epidermisStratum corneumCocciEpidermis