2024
Multilevel Implementation Strategies for Adolescent Human Papillomavirus Vaccine Uptake
Rutten L, Griffin J, St. Sauver J, MacLaughlin K, Austin J, Jenkins G, Herrin J, Jacobson R. Multilevel Implementation Strategies for Adolescent Human Papillomavirus Vaccine Uptake. JAMA Pediatrics 2024, 178: 29-36. PMID: 37983062, PMCID: PMC10957109, DOI: 10.1001/jamapediatrics.2023.4932.Peer-Reviewed Original ResearchConceptsAudit/feedbackReminder/recallHPV vaccine uptakeUsual careHPV vaccinationHPV vaccineVaccine uptakeHuman papillomavirusNational public health goalsHuman papillomavirus vaccine uptakeMultilevel implementation strategyHPV vaccination ratesPrimary care practicesHealth care professionalsEvidence-based interventionsPublic health goalsEvidence-based strategiesAdolescent vaccinesEligible patientsNew cancersPatient receiptVaccination ratesEligible childrenClinical trialsMayo Clinic
2022
Accuracy of Simulated Research Tasks by Community Hospitals Participating in a Multicenter Telemedicine Trial
Fang JL, Whyte H, Umoren R, Limjoco J, Makkar A, Yankanah R, McCoy M, Lo MD, Herrin J, Demaerschalk BM. Accuracy of Simulated Research Tasks by Community Hospitals Participating in a Multicenter Telemedicine Trial. Telemedicine Journal And E-Health 2022, 28: 1489-1495. PMID: 35167373, DOI: 10.1089/tmj.2021.0574.Peer-Reviewed Original ResearchConceptsHealth care professionalsCommunity hospitalCare professionalsStudy eligibilityClinical trialsEligibility criteriaStudy-eligible patientsSubsequent clinical trialsTelemedicine trialsTrial eligibility criteriaStandard descriptive statisticsEligible patientsNeonatal resuscitation scenarioTrial eligibilitySurvey response rateBACKGROUND/Clinical scenariosResponse rateHospitalTrialsResuscitation scenariosElectronic surveyEligibilityData elementsDescriptive statistics
2021
Real-world Cardiovascular Outcomes Associated With Degarelix vs Leuprolide for Prostate Cancer Treatment
Wallach JD, Deng Y, McCoy RG, Dhruva SS, Herrin J, Berkowitz A, Polley EC, Quinto K, Gandotra C, Crown W, Noseworthy P, Yao X, Shah ND, Ross JS, Lyon TD. Real-world Cardiovascular Outcomes Associated With Degarelix vs Leuprolide for Prostate Cancer Treatment. JAMA Network Open 2021, 4: e2130587. PMID: 34677594, PMCID: PMC8536955, DOI: 10.1001/jamanetworkopen.2021.30587.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsSecondary end pointsMyocardial infarctionClinical trialsCardiovascular diseaseProstate cancerCardiovascular eventsEnd pointRisk of MACELarge US administrative claims databasePropensity-matched cohort studyUS administrative claims databasePropensity score-matched patientsAdverse cardiovascular eventsPrimary end pointAdministrative claims databaseProportional hazards regressionRandomized clinical trialsAdministrative claims dataTrial eligibility criteriaMedicare Advantage beneficiariesProstate cancer treatmentReal-world evidenceElectronic health recordsCardiovascular outcomes
2020
Pragmatic cluster randomized trial to evaluate effectiveness and implementation of enhanced EHR-facilitated cancer symptom control (E2C2)
Finney Rutten LJ, Ruddy KJ, Chlan LL, Griffin JM, Herrin J, Leppin AL, Pachman DR, Ridgeway JL, Rahman PA, Storlie CB, Wilson PM, Cheville AL. Pragmatic cluster randomized trial to evaluate effectiveness and implementation of enhanced EHR-facilitated cancer symptom control (E2C2). Trials 2020, 21: 480. PMID: 32503661, PMCID: PMC7275300, DOI: 10.1186/s13063-020-04335-w.Peer-Reviewed Original ResearchConceptsPragmatic clusterSymptom controlCancer patientsEvidence-based implementation strategiesModerate sleep disturbanceInadequate symptom controlSelf-management supportRural-dwelling patientsLevel of careTeam of cliniciansElectronic health recordsMixed-methods evaluationClinical outcomesCare guidelinesPhysical functionSleep disturbancesCollaborative careClinical trialsHybrid type 2Care modelFunctional limitationsPatientsEHR algorithmType 2Clinical staff
2019
Effect of Collaborative Telerehabilitation on Functional Impairment and Pain Among Patients With Advanced-Stage Cancer
Cheville AL, Moynihan T, Herrin J, Loprinzi C, Kroenke K. Effect of Collaborative Telerehabilitation on Functional Impairment and Pain Among Patients With Advanced-Stage Cancer. JAMA Oncology 2019, 5: 644-652. PMID: 30946436, PMCID: PMC6512772, DOI: 10.1001/jamaoncol.2019.0011.Peer-Reviewed Original ResearchConceptsPharmacological pain managementAdvanced-stage cancerArm 2Pain managementQuality of lifePain interferenceBrief Pain InventoryAcademic medical centerHealth care systemHousehold ambulatorsHospital lengthStage IIICHome dischargeMost patientsMonth 3Pain InventoryPostacute careArm 3Blinded assessmentCollaborative careControl armClinical trialsCare teamFunctional impairmentHematologic cancers
2018
Evaluating the impact of multilevel evidence-based implementation strategies to enhance provider recommendation on human papillomavirus vaccination rates among an empaneled primary care patient population: a study protocol for a stepped-wedge cluster randomized trial
Finney Rutten LJ, Radecki Breitkopf C, St. Sauver JL, Croghan IT, Jacobson DJ, Wilson PM, Herrin J, Jacobson RM. Evaluating the impact of multilevel evidence-based implementation strategies to enhance provider recommendation on human papillomavirus vaccination rates among an empaneled primary care patient population: a study protocol for a stepped-wedge cluster randomized trial. Implementation Science 2018, 13: 96. PMID: 30001723, PMCID: PMC6043954, DOI: 10.1186/s13012-018-0778-x.Peer-Reviewed Original ResearchConceptsHPV vaccination ratesEvidence-based implementation strategiesStepped-wedge clusterVaccination ratesIntervention 1Human papillomavirusIntervention 2Human papillomavirus (HPV) vaccination ratesPrimary care patient populationPrimary care sitesProvider-level interventionsPractice-level interventionProcess evaluationAdolescent vaccinesBackgroundEach yearHPV vaccineMale patientsPrimary outcomePediatric populationPatient numbersPatient populationProvider recommendationStudy protocolClinical trialsBlock randomization
2017
Impact of Telemonitoring on Health Status
Jayaram NM, Khariton Y, Krumholz HM, Chaudhry SI, Mattera J, Tang F, Herrin J, Hodshon B, Spertus JA. Impact of Telemonitoring on Health Status. Circulation Cardiovascular Quality And Outcomes 2017, 10: e004148. PMID: 29237746, PMCID: PMC5776725, DOI: 10.1161/circoutcomes.117.004148.Peer-Reviewed Original ResearchConceptsKansas City Cardiomyopathy QuestionnaireUsual careHealth statusHeart failureKCCQ overall summary scoreRecent heart failure hospitalizationDisease-specific health statusKCCQ overall summaryHeart failure hospitalizationWeeks of dischargeRandomized clinical trialsOverall summary scoreKCCQ scoresNoninvasive TelemonitoringFailure hospitalizationBaseline characteristicsSecondary outcomesTreatment armsClinical trialsSummary scoresPatientsSubscale scoresCareHospitalizationScores
2014
Toward Spanning the Quality Chasm: An Examination of Team Functioning Measures
Strasser DC, Burridge AB, Falconer JA, Uomoto JM, Herrin J. Toward Spanning the Quality Chasm: An Examination of Team Functioning Measures. Archives Of Physical Medicine And Rehabilitation 2014, 95: 2220-2223. PMID: 25007707, DOI: 10.1016/j.apmr.2014.06.013.Peer-Reviewed Original ResearchConceptsPatient outcomesCommunity dischargeVeterans Affairs Medical CenterLength of stayClinical trialsMedical CenterModifiable attributesScale scoreInpatient teamsQuality ChasmStudy periodTime pointsOutcomesStayHigh rateScoresFunctioning measuresHigher scoresLower lengthExploratory analysisSuch findingsAssociationFurther research