2024
The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID
Krumholz H, Sawano M, Bhattacharjee B, Caraballo C, Khera R, Li S, Herrin J, Coppi A, Holub J, Henriquez Y, Johnson M, Goddard T, Rocco E, Hummel A, Al Mouslmani M, Putrino D, Carr K, Carvajal-Gonzalez S, Charnas L, De Jesus M, Ziegler F, Iwasaki A. The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID. The American Journal Of Medicine 2024 PMID: 38735354, DOI: 10.1016/j.amjmed.2024.04.030.Peer-Reviewed Original ResearchLC trialPROMIS-29Participants' homesTargeting viral persistencePlacebo-controlled trialDouble-blind studyElectronic health recordsCore Outcome MeasuresLong COVIDEQ-5D-5LRepeated measures analysisEvidence-based treatmentsPhase 2Double-blindParticipant-centred approachStudy drugPrimary endpointSecondary endpointsCommunity-dwellingHealth recordsHealthcare utilizationContiguous US statesViral persistencePatient groupDrug treatment
2006
Effectiveness of Diabetes Resource Nurse Case Management and Physician Profiling in a Fee-For-Service Setting: A Cluster Randomized Trial
Herrin J, Nicewander DA, Hollander PA, Couch CE, Winter FD, Haydar ZR, Warren SS, Ballard DJ. Effectiveness of Diabetes Resource Nurse Case Management and Physician Profiling in a Fee-For-Service Setting: A Cluster Randomized Trial. Baylor University Medical Center Proceedings 2006, 19: 95-102. PMID: 16609732, PMCID: PMC1426180, DOI: 10.1080/08998280.2006.11928137.Peer-Reviewed Original ResearchLow-density lipoprotein cholesterol levelsAnnual foot examMedical chart abstractionLipoprotein cholesterol levelsMedical record abstractionPrimary care physiciansNurse case managementAnnual eye examsNumber of patientsMedicare claims dataAnnual hemoglobinFoot examsPrimary endpointChart abstractionQuality improvement strategiesBlood pressureDiabetes mellitusEye examRecord abstractionRenal assessmentCare physiciansClinical outcomesResource nursesCare measuresCholesterol levels