2020
Association of Survival With Adjuvant Chemotherapy Among Patients With Early-Stage Non–Small Cell Lung Cancer With vs Without High-Risk Clinicopathologic Features
Pathak R, Goldberg SB, Canavan M, Herrin J, Hoag JR, Salazar MC, Papageorge M, Ermer T, Boffa DJ. Association of Survival With Adjuvant Chemotherapy Among Patients With Early-Stage Non–Small Cell Lung Cancer With vs Without High-Risk Clinicopathologic Features. JAMA Oncology 2020, 6: 1741-1750. PMID: 32940636, PMCID: PMC7499246, DOI: 10.1001/jamaoncol.2020.4232.Peer-Reviewed Original ResearchConceptsNode-negative non-small cell lung cancerHigh-risk pathologic featuresNon-small cell lung cancerAdjuvant chemotherapyCell lung cancerPathologic featuresTumor sizeSurvival benefitCohort studyLung cancerNode-negative NSCLCEarly-stage non-small cell lung cancerCox proportional hazards regression modelHigh-risk clinicopathologic featuresProportional hazards regression modelsNational Cancer DatabaseRetrospective cohort studyTreatment-naive patientsAdjuvant chemotherapy useHigh-risk featuresAssociation of survivalHazards regression modelsImmortal time biasChemotherapy useEligible patients
2013
Immediate Open Repair vs Surveillance in Patients with Small Abdominal Aortic Aneurysms: Survival Differences by Aneurysm Size
Filardo G, Lederle FA, Ballard DJ, Hamilton C, da Graca B, Herrin J, Harbor J, VanBuskirk JB, Johnson GR, Powell JT. Immediate Open Repair vs Surveillance in Patients with Small Abdominal Aortic Aneurysms: Survival Differences by Aneurysm Size. Mayo Clinic Proceedings 2013, 88: 910-919. PMID: 24001483, DOI: 10.1016/j.mayocp.2013.05.014.Peer-Reviewed Original ResearchConceptsImmediate open repairAbdominal aortic aneurysmOpen repairSurvival differencesAAA sizeSurvival benefitAortic aneurysmUK Small Aneurysm TrialAsymptomatic abdominal aortic aneurysmLarge abdominal aortic aneurysmSmall asymptomatic abdominal aortic aneurysmsSmall abdominal aortic aneurysmsImmediate endovascular repairNonclinical risk factorsSignificant survival benefitFirst-line managementSignificant survival differenceProportional hazards modelEndovascular repairSurveillance patientsAdjusted analysisStudy cohortAneurysm TrialRecent trialsRisk factors