2022
Perioperative magnetic resonance imaging in breast cancer care: Distinct adoption trajectories among physician patient-sharing networks
Xu X, Soulos PR, Herrin J, Wang SY, Pollack CE, Killelea BK, Forman HP, Gross CP. Perioperative magnetic resonance imaging in breast cancer care: Distinct adoption trajectories among physician patient-sharing networks. PLOS ONE 2022, 17: e0265188. PMID: 35290417, PMCID: PMC8923453, DOI: 10.1371/journal.pone.0265188.Peer-Reviewed Original ResearchMeSH KeywordsAgedBreast NeoplasmsFemaleHumansMagnetic Resonance ImagingMastectomyMedicarePhysiciansPractice Patterns, Physicians'United StatesConceptsPhysician patient-sharing networksPerioperative magnetic resonance imagingClinical risk factorsMagnetic resonance imagingPatient clinical risk factorsPatient-sharing networksBreast cancer careRisk-adjusted ratesMastectomy usePhysician networksCancer careRisk factorsEnd Results-Medicare databaseCharacteristics of patientsProportion of patientsBreast cancer surgeryComposition of patientsMRI adoptionDistinct trajectoriesMore patientsCancer surgeryClinical outcomesCancer specialistsMRI usePatientsAssociation Between Payments by Pharmaceutical Manufacturers and Prescribing Behavior in Rheumatology
Duarte-García A, Crowson CS, McCoy RG, Herrin J, Lam V, Putman MS, Ross JS, Matteson EL, Shah ND. Association Between Payments by Pharmaceutical Manufacturers and Prescribing Behavior in Rheumatology. Mayo Clinic Proceedings 2022, 97: 250-260. PMID: 35120693, PMCID: PMC9013005, DOI: 10.1016/j.mayocp.2021.08.026.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesDrug CostsDrug IndustryHumansMedicare Part DPractice Patterns, Physicians'Prescription DrugsRetrospective StudiesRheumatologyUnited States
2021
Uptake of evidence by physicians: De-adoption of erythropoiesis-stimulating agents after the TREAT trial
Vu K, Zhou J, Everhart A, Desai N, Herrin J, Jena AB, Ross JS, Shah ND, Karaca-Mandic P. Uptake of evidence by physicians: De-adoption of erythropoiesis-stimulating agents after the TREAT trial. BMC Nephrology 2021, 22: 284. PMID: 34419007, PMCID: PMC8379779, DOI: 10.1186/s12882-021-02491-y.Peer-Reviewed Original ResearchConceptsErythropoiesis-stimulating agentsChronic kidney diseaseEpoetin alfaDarbepoetin alfaTREAT trialTypes of ESAsNew clinical evidencePrimary care physiciansMedicare AdvantageUptake of evidenceCare physiciansAnemia treatmentClinical evidenceKidney diseasePhysician genderMedicare feeUnsafe treatmentSegmented regression approachStudy periodPhysiciansService populationConsistent changesAlfaHigher useTreatmentPhysician variation in the de‐adoption of ineffective statin and fibrate therapy
Everhart A, Desai NR, Dowd B, Herrin J, Higuera L, Jeffery MM, Jena AB, Ross JS, Shah ND, Smith LB, Karaca‐Mandic P. Physician variation in the de‐adoption of ineffective statin and fibrate therapy. Health Services Research 2021, 56: 919-931. PMID: 33569804, PMCID: PMC8522575, DOI: 10.1111/1475-6773.13630.Peer-Reviewed Original ResearchMeSH KeywordsAgedDiabetes Mellitus, Type 2Drug Therapy, CombinationDrug UtilizationFemaleFibric AcidsGuideline AdherenceHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypoglycemic AgentsHypolipidemic AgentsLongitudinal StudiesMaleMedicare Part CMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Risk FactorsUnited StatesConceptsMedicare Advantage patientsType 2 diabetic patientsACCORD lipid trialFibrate useAdvantage patientsCommercial patientsPhysician characteristicsLIPID trialFibrate therapyDiabetic patientsPhysician variationDiabetes careType 2 diabetes diagnosisContinuous insurance enrollmentPatient diabetes carePhysician random effectsGlucose-lowering drugsElectronic health record dataHealth record dataReal-world data assetConcurrent statinCardiovascular eventsStatin usersClinical evidenceManagement visits
2020
Physician trajectories of abandoning long‐course breast radiotherapy and their cost impact
Xu X, Soulos PR, Herrin J, Wang S, Pollack CE, Evans SB, Yu JB, Gross CP. Physician trajectories of abandoning long‐course breast radiotherapy and their cost impact. Health Services Research 2020, 56: 497-506. PMID: 33070305, PMCID: PMC8143683, DOI: 10.1111/1475-6773.13572.Peer-Reviewed Original ResearchMeSH KeywordsAgedBreast NeoplasmsFemaleHumansInsurance Claim ReviewMastectomy, SegmentalMedicarePeer GroupPhysiciansPractice Patterns, Physicians'Radiotherapy, AdjuvantRetrospective StudiesUnited StatesConceptsPhysician peer groupsWhole breast irradiationCF-WBIRisk-adjusted ratesBreast radiotherapyPractice patternsLow useChronic Conditions Data WarehouseDistinct practice patternsPatients' clinical characteristicsSetting of radiotherapyAdjuvant breast radiotherapyYears of ageDistinct trajectoriesImportant cost implicationsHigher useAdjuvant radiotherapyClinical characteristicsEligible womenBreast cancerCost implicationsLatent class growth analysisService beneficiariesMedicare programRadiotherapyPatient and provider-level factors associated with changes in utilization of treatments in response to evidence on ineffectiveness or harm
Smith LB, Desai NR, Dowd B, Everhart A, Herrin J, Higuera L, Jeffery MM, Jena AB, Ross JS, Shah ND, Karaca-Mandic P. Patient and provider-level factors associated with changes in utilization of treatments in response to evidence on ineffectiveness or harm. International Journal Of Health Economics And Management 2020, 20: 299-317. PMID: 32350680, PMCID: PMC7725279, DOI: 10.1007/s10754-020-09282-2.Peer-Reviewed Original ResearchConceptsPermanent atrial fibrillationType 2 diabetesAtrial fibrillationPermanent atrial fibrillation patientsProvider-level factorsAtrial fibrillation patientsEffective new therapiesPrimary care providersUse of medicationsProvider-level characteristicsUtilization of treatmentHigh-quality health careDronedarone useInterrupted time-series regression modelsFibrillation patientsMedication useDiabetes patientsProvider characteristicsCare providersMedicare feeNew therapiesService claimsFemale providersPatientsMedications
2019
Prevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project
Mahajan S, Zhang D, He S, Lu Y, Gupta A, Spatz ES, Lu J, Huang C, Herrin J, Liu S, Yang J, Wu C, Cui J, Zhang Q, Li X, Nasir K, Zheng X, Krumholz HM, Li J, Dong Z, Jiang B, Zhang Y, Liu Y, Meng Y, Xi Y, Tian Y, Fu Y, Liu T, Yan S, Jin L, Wang J, Xu X, Xing X, Zhang L, Fang X, Xu Y, Xu C, Fan L, Qi M, Qi J, Li J, Liu Q, Feng Y, Wang J, Wen H, Xu J, He J, Jiang C, Yang C, Yu Y, Tashi Z, Hu Z, Zhang J, Li X, Ma S, Ma Y, Huang Y, Zhang Y, Shen J. Prevalence, Awareness, and Treatment of Isolated Diastolic Hypertension: Insights From the China PEACE Million Persons Project. Journal Of The American Heart Association 2019, 8: e012954. PMID: 31566101, PMCID: PMC6806046, DOI: 10.1161/jaha.119.012954.Peer-Reviewed Original ResearchConceptsMillion Persons ProjectPrior cardiovascular eventsBody mass indexAntihypertensive medicationsDiastolic hypertensionCardiovascular eventsDiabetes mellitusMass indexIsolated diastolic hypertensionDiastolic blood pressureSelf-reported diagnosisTreatment of peoplePersons ProjectBlood pressureTreatment patternsHypertensionLeast collegeHigher likelihoodMellitusMedicationsPrevalenceTreatmentDiagnosisSubstantial numberCurrent useAssociation Between Degrees of Separation in Physician Networks and Surgeons’ Use of Perioperative Breast Magnetic Resonance Imaging
Shi Y, Pollack CE, Soulos PR, Herrin J, Christakis NA, Xu X, Gross CP. Association Between Degrees of Separation in Physician Networks and Surgeons’ Use of Perioperative Breast Magnetic Resonance Imaging. Medical Care 2019, 57: 460-467. PMID: 31008899, PMCID: PMC6522278, DOI: 10.1097/mlr.0000000000001123.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBreast NeoplasmsFemaleHumansMagnetic Resonance ImagingMedicarePerioperative CarePractice Patterns, Physicians'Retrospective StudiesSurgeonsUnited StatesConceptsBreast magnetic resonance imagingMagnetic resonance imagingPerioperative magnetic resonance imagingMRI useResonance imagingSurgeons' useBreast cancer carePatient-sharing networksPractice of surgeonsPairs of surgeonsUnproven benefitRetrospective studyPhysician pairsCancer carePractice patternsBreast cancerMRI utilizationMedicare dataSurgical colleaguesPatientsSurgeonsStudy periodPhysician networksCareAssociation
2018
Surgeon peer network characteristics and adoption of new imaging techniques in breast cancer: A study of perioperative MRI
Tannenbaum SS, Soulos PR, Herrin J, Pollack CE, Xu X, Christakis NA, Forman HP, Yu JB, Killelea BK, Wang S, Gross CP. Surgeon peer network characteristics and adoption of new imaging techniques in breast cancer: A study of perioperative MRI. Cancer Medicine 2018, 7: 5901-5909. PMID: 30444005, PMCID: PMC6308117, DOI: 10.1002/cam4.1821.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBreast NeoplasmsFemaleHumansMagnetic Resonance ImagingMedicarePeer GroupPerioperative PeriodPractice Patterns, Physicians'SEER ProgramSurgeonsUnited StatesConceptsPrimary care physiciansPatient-sharing networksBreast cancerPerioperative MRISubsequent receiptNon-cancer patientsBreast cancer practiceMultivariable hierarchical modelsUse of MRIClinical characteristicsCare physiciansFemale patientsCancer practiceMedicare databaseNew imaging techniquesMedicare sampleStage 0Claims dataPatientsPhysician groupsMRISurgeonsCancerEquivocal evidencePhysicians
2017
The Impact of Social Contagion on Physician Adoption of Advanced Imaging Tests in Breast Cancer
Pollack CE, Soulos PR, Herrin J, Xu X, Christakis NA, Forman HP, Yu JB, Killelea BK, Wang SY, Gross CP. The Impact of Social Contagion on Physician Adoption of Advanced Imaging Tests in Breast Cancer. Journal Of The National Cancer Institute 2017, 109: djw330. PMID: 28376191, PMCID: PMC6059114, DOI: 10.1093/jnci/djw330.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingBaseline usePositron emission tomography scanEnd Results-MedicareEmission tomography scanBreast cancer practiceImaging modalitiesAdvanced imaging testsHierarchical logistic regression modelsLogistic regression modelsPatient characteristicsUnproven benefitCancer practiceMRI/PETTomography scanBreast cancerMRI useImaging testsClinical practicePET useResonance imagingPET imagingPhysician peersPhysician adoptionBaseline period
2015
Shared Decision Making for Antidepressants in Primary Care: A Cluster Randomized Trial
LeBlanc A, Herrin J, Williams MD, Inselman JW, Branda ME, Shah ND, Heim EM, Dick SR, Linzer M, Boehm DH, Dall-Winther KM, Matthews MR, Yost KJ, Shepel KK, Montori VM. Shared Decision Making for Antidepressants in Primary Care: A Cluster Randomized Trial. JAMA Internal Medicine 2015, 175: 1761-1770. PMID: 26414670, PMCID: PMC4754973, DOI: 10.1001/jamainternmed.2015.5214.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntidepressive AgentsChoice BehaviorCluster AnalysisComparative Effectiveness ResearchDecision MakingDecision Support TechniquesDepressionFemaleHumansMaleMedication AdherenceMiddle AgedMinnesotaOutcome Assessment, Health CarePatient ParticipationPractice Patterns, Physicians'Primary Health CarePsychiatric Status Rating ScalesWisconsinConceptsPrimary care practicesDecisional comfortMedication adherenceUsual careDepression outcomesPrimary careSevere depressionCare practicesComparative effectivenessUrban primary care practicesEncounter decision aidsTrials of adultsPrimary care cliniciansPatient Health QuestionnaireTreatment of depressionPatient-centered careQuality of careTranslation of evidenceCluster Randomized TrialDecision aidEffects of DMCUse of DMCAvailable antidepressantsCare cliniciansMedication choice
2014
Toward Spanning the Quality Chasm: An Examination of Team Functioning Measures
Strasser DC, Burridge AB, Falconer JA, Uomoto JM, Herrin J. Toward Spanning the Quality Chasm: An Examination of Team Functioning Measures. Archives Of Physical Medicine And Rehabilitation 2014, 95: 2220-2223. PMID: 25007707, DOI: 10.1016/j.apmr.2014.06.013.Peer-Reviewed Original ResearchMeSH KeywordsAdultFemaleHumansLeadershipLength of StayMaleMiddle AgedPatient Care TeamPatient DischargePatient Outcome AssessmentPractice Patterns, Physicians'Quality ImprovementRecovery of FunctionRehabilitationConceptsPatient outcomesCommunity dischargeVeterans Affairs Medical CenterLength of stayClinical trialsMedical CenterModifiable attributesScale scoreInpatient teamsQuality ChasmStudy periodTime pointsOutcomesStayHigh rateScoresFunctioning measuresHigher scoresLower lengthExploratory analysisSuch findingsAssociationFurther research
2013
Variation in Receipt of Radiation Therapy After Breast-conserving Surgery
Feinstein AJ, Soulos PR, Long JB, Herrin J, Roberts KB, Yu JB, Gross CP. Variation in Receipt of Radiation Therapy After Breast-conserving Surgery. Medical Care 2013, 51: 330-338. PMID: 23151590, PMCID: PMC3596448, DOI: 10.1097/mlr.0b013e31827631b0.Peer-Reviewed Original ResearchConceptsUse of RTShort life expectancyRadiation therapyBreast cancerLife expectancyPrimary surgeonStage I breast cancerEarly-stage breast cancerRadiation oncologist densityAdjuvant radiation therapyI breast cancerReceipt of radiationBreast-conserving surgeryImpact of physiciansHierarchical logistic regression modelsLogistic regression modelsLonger life expectancyLE patientsRetrospective cohortLE groupOlder womenPatientsTreatment ratesWomenCancerAssociation between physicians’ experience after training and maternal obstetrical outcomes: cohort study
Epstein AJ, Srinivas SK, Nicholson S, Herrin J, Asch DA. Association between physicians’ experience after training and maternal obstetrical outcomes: cohort study. The BMJ 2013, 346: f1596. PMID: 23538919, PMCID: PMC3610558, DOI: 10.1136/bmj.f1596.Peer-Reviewed Original ResearchConceptsMaternal complication ratesMaternal complicationsComplication rateRetrospective cohort analysisAcute care hospitalsObstetrical outcomesCesarean deliveryCohort studyCare hospitalVaginal deliveryCesarean birthCompletion of residencyCohort analysisPhysician yearsMAIN OUTCOMEThird decadePost-residency practiceComplicationsObstetriciansMore yearsSecular trendsComposite measurePercentage pointsAssociationSecond decade
2005
Quality Improvement Efforts and Hospital Performance
Bradley EH, Herrin J, Mattera JA, Holmboe ES, Wang Y, Frederick P, Roumanis SA, Radford MJ, Krumholz HM. Quality Improvement Efforts and Hospital Performance. Medical Care 2005, 43: 282-292. PMID: 15725985, DOI: 10.1097/00005650-200503000-00011.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAged, 80 and overCross-Sectional StudiesDrug Utilization ReviewFemaleHospitalsHumansLeadershipMaleMedical Staff, HospitalMiddle AgedMyocardial InfarctionOrganizational CultureOutcome Assessment, Health CarePractice Patterns, Physicians'Quality Indicators, Health CareRegistriesTotal Quality ManagementUnited StatesConceptsAcute myocardial infarctionBeta-blocker prescription ratesQuality improvement effortsMyocardial infarctionBeta-blocker useHospital teaching statusCross-sectional studyQuality improvement interventionsPatient-level dataPhysician leadershipQuality of careHospital performanceHospital quality improvement effortsImprovement effortsQuality improvement strategiesPrescription ratesBorderline significanceNational registryAMI volumeUS hospitalsImprovement interventionsHospitalTeaching statusEvidence baseHigh/medium
2002
The relation between methods and recommendations in clinical practice guidelines for hypertension and hyperlipidemia.
Fretheim A, Williams JW, Oxman AD, Herrin J. The relation between methods and recommendations in clinical practice guidelines for hypertension and hyperlipidemia. The Journal Of Family Practice 2002, 51: 963-8. PMID: 12485552.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedEvaluation Studies as TopicEvidence-Based MedicineFamily PracticeFemaleGuideline AdherenceHealth Planning GuidelinesHumansHyperlipidemiasHypertensionMaleMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Quality of Health CareRisk AssessmentSensitivity and SpecificitySeverity of Illness IndexVirginiaConceptsClinical practice guidelinesPractice guidelinesDrug selectionTreatment thresholdSpecialty societiesInitial drug selectionCholesterol screeningGuideline developersSystematic reviewHypertensionHyperlipidemiaAggressive recommendationsGuidelinesWide variationGuideline methodsRecommendationsCriteriaCluster randomised controlled trial of tailored interventions to improve the management of urinary tract infections in women and sore throat
Flottorp S, Oxman A, Håvelsrud K, Treweek S, Herrin J. Cluster randomised controlled trial of tailored interventions to improve the management of urinary tract infections in women and sore throat. The BMJ 2002, 325: 367. PMID: 12183309, PMCID: PMC117890, DOI: 10.1136/bmj.325.7360.367.Peer-Reviewed Original ResearchConceptsUrinary tract infectionTract infectionsSore throatTelephone consultationsThroat groupUrinary tract infection groupLaboratory testsAntibiotic prescriptionsPatient educational materialsRate of useInfection groupGeneral practitionersIntervention groupPractice assistantsOutcome measuresGeneral practiceComplex interventionsInfectionInterventionWomenSignificant differencesConsultationTrialsThroatAntibiotics