2020
Pragmatic cluster randomized trial to evaluate effectiveness and implementation of enhanced EHR-facilitated cancer symptom control (E2C2)
Finney Rutten LJ, Ruddy KJ, Chlan LL, Griffin JM, Herrin J, Leppin AL, Pachman DR, Ridgeway JL, Rahman PA, Storlie CB, Wilson PM, Cheville AL. Pragmatic cluster randomized trial to evaluate effectiveness and implementation of enhanced EHR-facilitated cancer symptom control (E2C2). Trials 2020, 21: 480. PMID: 32503661, PMCID: PMC7275300, DOI: 10.1186/s13063-020-04335-w.Peer-Reviewed Original ResearchConceptsPragmatic clusterSymptom controlCancer patientsEvidence-based implementation strategiesModerate sleep disturbanceInadequate symptom controlSelf-management supportRural-dwelling patientsLevel of careTeam of cliniciansElectronic health recordsMixed-methods evaluationClinical outcomesCare guidelinesPhysical functionSleep disturbancesCollaborative careClinical trialsHybrid type 2Care modelFunctional limitationsPatientsEHR algorithmType 2Clinical staff
2015
Shared Decision Making for Antidepressants in Primary Care: A Cluster Randomized Trial
LeBlanc A, Herrin J, Williams MD, Inselman JW, Branda ME, Shah ND, Heim EM, Dick SR, Linzer M, Boehm DH, Dall-Winther KM, Matthews MR, Yost KJ, Shepel KK, Montori VM. Shared Decision Making for Antidepressants in Primary Care: A Cluster Randomized Trial. JAMA Internal Medicine 2015, 175: 1761-1770. PMID: 26414670, PMCID: PMC4754973, DOI: 10.1001/jamainternmed.2015.5214.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntidepressive AgentsChoice BehaviorCluster AnalysisComparative Effectiveness ResearchDecision MakingDecision Support TechniquesDepressionFemaleHumansMaleMedication AdherenceMiddle AgedMinnesotaOutcome Assessment, Health CarePatient ParticipationPractice Patterns, Physicians'Primary Health CarePsychiatric Status Rating ScalesWisconsinConceptsPrimary care practicesDecisional comfortMedication adherenceUsual careDepression outcomesPrimary careSevere depressionCare practicesComparative effectivenessUrban primary care practicesEncounter decision aidsTrials of adultsPrimary care cliniciansPatient Health QuestionnaireTreatment of depressionPatient-centered careQuality of careTranslation of evidenceCluster Randomized TrialDecision aidEffects of DMCUse of DMCAvailable antidepressantsCare cliniciansMedication choice
2014
A reanalysis of cluster randomized trials showed interrupted time-series studies were valuable in health system evaluation
Fretheim A, Zhang F, Ross-Degnan D, Oxman AD, Cheyne H, Foy R, Goodacre S, Herrin J, Kerse N, McKinlay RJ, Wright A, Soumerai SB. A reanalysis of cluster randomized trials showed interrupted time-series studies were valuable in health system evaluation. Journal Of Clinical Epidemiology 2014, 68: 324-333. PMID: 25499983, DOI: 10.1016/j.jclinepi.2014.10.003.Peer-Reviewed Original ResearchConceptsC-RCTsControl groupInterrupted time series studyConfidence intervalsConcurrent control groupHealth system interventionsHealth system evaluationControl arm dataInterrupted time series designIntervention armRandomized trialsControl group dataTrial dataTime-series studyTime series designHealth systemStudy designEffect estimatesTrialsInterventionSystem interventionsArm dataGroup dataRCTsGroup
2002
Blind Faith? The Effects of Promoting Active Sick Leave for Back Pain Patients
Scheel I, Hagen K, Herrin J, Carling C, Oxman A. Blind Faith? The Effects of Promoting Active Sick Leave for Back Pain Patients. Spine 2002, 27: 2734-2740. PMID: 12461401, DOI: 10.1097/00007632-200212010-00014.Peer-Reviewed Original ResearchConceptsLow back painProportion of patientsQuality of lifeSick leaveControl groupIntervention groupPassive intervention groupBack pain patientsPassive interventionMain outcome measuresSelf-reported qualityNational Insurance AdministrationLBP patientsPain patientsBack painPatient satisfactionGeneral practitionersMedian numberOutcome measuresBACKGROUND DATAIndividual patientsPatientsResponse rateHealth outcomesInterventionCluster randomised controlled trial of tailored interventions to improve the management of urinary tract infections in women and sore throat
Flottorp S, Oxman A, Håvelsrud K, Treweek S, Herrin J. Cluster randomised controlled trial of tailored interventions to improve the management of urinary tract infections in women and sore throat. The BMJ 2002, 325: 367. PMID: 12183309, PMCID: PMC117890, DOI: 10.1136/bmj.325.7360.367.Peer-Reviewed Original ResearchConceptsUrinary tract infectionTract infectionsSore throatTelephone consultationsThroat groupUrinary tract infection groupLaboratory testsAntibiotic prescriptionsPatient educational materialsRate of useInfection groupGeneral practitionersIntervention groupPractice assistantsOutcome measuresGeneral practiceComplex interventionsInfectionInterventionWomenSignificant differencesConsultationTrialsThroatAntibioticsA Call for Action
Scheel I, Hagen K, Herrin J, Oxman A. A Call for Action. Spine 2002, 27: 561-566. PMID: 11884902, DOI: 10.1097/00007632-200203150-00002.Peer-Reviewed Original ResearchConceptsLow back painGeneral practitionersBack painPassive interventionSick leaveBack pain patientsClinical practice guidelinesMain outcome measuresProactive interventionsEligible patientsPain patientsIntervention municipalitiesEarly returnGP practicesPractice guidelinesBACKGROUND DATAOutcome measuresPatientsControl groupPainTelephone callsCommunity interventionsControl municipalitiesInterventionImportance of advice
2000
Quality improvement studies: the need is there but so are the challenges
Krumholz H, Herrin J. Quality improvement studies: the need is there but so are the challenges. The American Journal Of Medicine 2000, 109: 501-503. PMID: 11042244, DOI: 10.1016/s0002-9343(00)00593-3.Peer-Reviewed Original Research