Src‐family protein tyrosine kinase (SFK) stimulates KCNJ10 K channels in the basolateral membrane of distal convoluted tubules (DCT).
Wang W, Zhang C, Lin D, Yue P, Wang L, Rinehart J. Src‐family protein tyrosine kinase (SFK) stimulates KCNJ10 K channels in the basolateral membrane of distal convoluted tubules (DCT). The FASEB Journal 2013, 27: 911.1-911.1. DOI: 10.1096/fasebj.27.1_supplement.911.1.Peer-Reviewed Original ResearchSrc family protein tyrosine kinasesPhosphorylation sitesWhole-cell K currentsTyrosine phosphorylationTyr-8Tyr-9Tyrosine phosphorylation sitesProtein tyrosine kinasesTyrosine phosphorylated proteinsBasolateral K channelsPhosphorylated proteinsBasolateral Cl(-) exitSFK activityHigh K dietTyrosine kinaseK channelsPhysiological roleHEK293 cellsCl exitHEK cellsDCT1Patch-clamp experimentsBasolateral membraneKCNJ10Phosphorylation