1984
Autoantibodies to the U2 small nuclear ribonucleoprotein in a patient with scleroderma-polymyositis overlap syndrome.
Mimori T, Hinterberger M, Pettersson I, Steitz JA. Autoantibodies to the U2 small nuclear ribonucleoprotein in a patient with scleroderma-polymyositis overlap syndrome. Journal Of Biological Chemistry 1984, 259: 560-565. PMID: 6231285, DOI: 10.1016/s0021-9258(17)43698-2.Peer-Reviewed Original ResearchConceptsU2 small nuclear ribonucleoproteinSmall nuclear ribonucleoproteinNuclear ribonucleoproteinU2 small nuclear RNASm small nuclear ribonucleoproteinsU6 small nuclear ribonucleoproteinProtein blot analysisSmall nuclear RNAScleroderma-polymyositis overlap syndromeU1 small nuclear ribonucleoproteinHeLa cell extractsRNA speciesNuclear RNAB proteinCell extractsProtein bandsBlot analysisOverlap syndromeRibonucleoproteinProteinAnti-Sm antibodiesU1InsectsRNAPolypeptide
1981
Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease.
Lerner EA, Lerner MR, Janeway CA, Steitz JA. Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 1981, 78: 2737-2741. PMID: 6789322, PMCID: PMC319432, DOI: 10.1073/pnas.78.5.2737.Peer-Reviewed Original ResearchConceptsAnti-Sm antibodiesMonoclonal anti-Sm antibodyAutoimmune diseasesMonoclonal antibodiesLupus erythematosus-like syndromeMRL/Mp-lpr/lprProduction of autoantibodiesPatient seraSpleen cellsImmunofluorescence techniqueAntibodiesSP 2/0Competition radioimmunoassayImmunoprecipitation patternsCell linesSm antigenAntigenDiseaseMiceCellular constituentsCellular componentsAutoantibodiesPatientsLupusSyndrome