2014
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
Cech TR, Steitz JA. The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones. Cell 2014, 157: 77-94. PMID: 24679528, DOI: 10.1016/j.cell.2014.03.008.Peer-Reviewed Original ResearchConceptsBiological functionsRNA-protein complexesLevel of transcriptionForeign nucleic acidsMost ncRNAsLong ncRNAsNcRNA researchRNA processingGenome rearrangementsNucleic acidsNoncoding RNAsGene expressionRNA structureNcRNAsBase pairingDNA synthesisRemarkable varietySnoRNPsRiboswitchGenomeSnRNPsRNAsRibosomesTranscriptionTelomerase
2002
Exclusive Interaction of the 15.5 kD Protein with the Terminal Box C/D Motif of a Methylation Guide snoRNP
Szewczak LB, DeGregorio SJ, Strobel SA, Steitz JA. Exclusive Interaction of the 15.5 kD Protein with the Terminal Box C/D Motif of a Methylation Guide snoRNP. Cell Chemical Biology 2002, 9: 1095-1107. PMID: 12401494, DOI: 10.1016/s1074-5521(02)00239-9.Peer-Reviewed Original ResearchConceptsBox C/D motifKD proteinD motifBox C/D snoRNAsBox C/D snoRNPsSite-specific methylationSpliceosomal RNAsDeleterious substitutionsD snoRNAsD snoRNPsBox DExclusive interactionsInteraction sitesXenopus oocytesSnoRNPsProteinMotifSnoRNAsVivoMethylationA89Single interaction siteRNAExocyclic amineOocytesSite‐specific cross‐linking analyses reveal an asymmetric protein distribution for a box C/D snoRNP
Cahill NM, Friend K, Speckmann W, Li Z, Terns RM, Terns MP, Steitz JA. Site‐specific cross‐linking analyses reveal an asymmetric protein distribution for a box C/D snoRNP. The EMBO Journal 2002, 21: 3816-3828. PMID: 12110593, PMCID: PMC126121, DOI: 10.1093/emboj/cdf376.Peer-Reviewed Original ResearchConceptsBox C/D snoRNPsD snoRNPsC-boxBox C/D classSite-specific cross-linking analysisBox C/D small nucleolar ribonucleoproteinsBox C/DAsymmetric protein distributionSmall nucleolar ribonucleoproteinSmall nucleolar RNAsXenopus oocyte nucleusCross-linking analysisNucleolar RNAsNucleolar ribonucleoproteinD motifBox DMutational analysisOocyte nucleusGuide sequenceWidespread modificationProtein distributionFibrillarinFunctional rescueCore proteinSnoRNPs
1999
Guided tours: from precursor snoRNA to functional snoRNP
Weinstein L, Steitz J. Guided tours: from precursor snoRNA to functional snoRNP. Current Opinion In Cell Biology 1999, 11: 378-384. PMID: 10395551, DOI: 10.1016/s0955-0674(99)80053-2.Peer-Reviewed Original Research