2004
Guide RNAs with 5′ Caps and Novel Box C/D snoRNA-like Domains for Modification of snRNAs in Metazoa
Tycowski KT, Aab A, Steitz JA. Guide RNAs with 5′ Caps and Novel Box C/D snoRNA-like Domains for Modification of snRNAs in Metazoa. Current Biology 2004, 14: 1985-1995. PMID: 15556860, DOI: 10.1016/j.cub.2004.11.003.Peer-Reviewed Original ResearchConceptsModification guide RNAsGuide RNABox C/D snoRNAsInvariant G residueKink-turn structureGuide RNA genesShort guide RNASmall ribonucleoprotein particlesMetazoan organismsAncestral metazoanGuanosine capMetazoan cellsSingle intronD snoRNAsRNA genesSpliceosomal snRNAsTelomerase RNARibosomal RNASuch RNAsRibonucleoprotein particleMetazoansUpstream promoterIntronsG residuesCommon modification
2001
Non-coding snoRNA host genes in Drosophila: expression strategies for modification guide snoRNAs
Tycowski K, Steitz J. Non-coding snoRNA host genes in Drosophila: expression strategies for modification guide snoRNAs. European Journal Of Cell Biology 2001, 80: 119-125. PMID: 11302516, DOI: 10.1078/0171-9335-00150.Peer-Reviewed Original ResearchConceptsSnoRNA host genesModification-guide snoRNAsHost genesGuide snoRNAsSplice siteDifferent eukaryotic kingdomsEukaryotic kingdomsPolycistronic unitsD. melanogasterProtein codingTranslational apparatusConserved distanceSnoRNA sequencesTrailer sequencesIntron lariatPrimary transcriptFunctional proteinsNucleotides upstreamExpression strategyExonucleolytic activitySnoRNAsIntronsGenesDebranching activityProtein
1992
Splicing Takes a Holliday
Steitz J. Splicing Takes a Holliday. Science 1992, 257: 888-889. PMID: 1386941, DOI: 10.1126/science.1386941.Peer-Reviewed Original Research