2016
Intronless β-Globin Reporter: A Tool for Studying Nuclear RNA Stability Elements
Brown JA, Steitz JA. Intronless β-Globin Reporter: A Tool for Studying Nuclear RNA Stability Elements. Methods In Molecular Biology 2016, 1428: 77-92. PMID: 27236793, PMCID: PMC5547891, DOI: 10.1007/978-1-4939-3625-0_5.Peer-Reviewed Original ResearchMeSH KeywordsBeta-GlobinsCell NucleusCloning, MolecularGenes, ReporterHEK293 CellsHumansIntronsNucleic Acid ConformationRNA StabilityRNA, Messenger
1998
Classification of gas5 as a Multi-Small-Nucleolar-RNA (snoRNA) Host Gene and a Member of the 5′-Terminal Oligopyrimidine Gene Family Reveals Common Features of snoRNA Host Genes
Smith C, Steitz J. Classification of gas5 as a Multi-Small-Nucleolar-RNA (snoRNA) Host Gene and a Member of the 5′-Terminal Oligopyrimidine Gene Family Reveals Common Features of snoRNA Host Genes. Molecular And Cellular Biology 1998, 18: 6897-6909. PMID: 9819378, PMCID: PMC109273, DOI: 10.1128/mcb.18.12.6897.Peer-Reviewed Original ResearchMeSH Keywords3T3 CellsAnimalsBase SequenceCell DivisionCell NucleolusCloning, MolecularHumansMembrane ProteinsMiceMolecular Sequence DataMultigene FamilyProtein BiosynthesisRibonucleoproteinsRibosomesRNA SplicingRNA, AntisenseRNA, MessengerRNA, Small NuclearRNA, Small NucleolarTranscription, GeneticConceptsHost genesGene familyGAS5 geneBox C/D snoRNAsSnoRNA host genesHost gene transcriptsCell growthInhibition of translationSmall nucleolar RNA host geneSmall nucleolarD snoRNAsGAS5 transcriptsMRNP particlesSpecific transcriptsGene transcriptsGenesTranscriptsSnoRNAsRNASequenceIntronsCommon featureRibosomesRRNAFamily
1995
Isolation and characterization of a novel, low abundance hnRNP protein: A0.
Myer VE, Steitz JA. Isolation and characterization of a novel, low abundance hnRNP protein: A0. RNA 1995, 1: 171-82. PMID: 7585247, PMCID: PMC1369071.Peer-Reviewed Original ResearchConceptsHnRNP A0HnRNP proteinsGlycine-rich C-terminusHeterogeneous nuclear ribonucleoprotein complexesB familyLow-abundance membersPre-messenger RNATwo-dimensional gel electrophoresisCharacteristic primary structureNuclear ribonucleoprotein complexesVariety of proteinsB family membersRibonucleoprotein complexesHnRNP complexesMammalian cellsMRNA stabilityC-terminusPrimary structureProtease mappingProteinRNA probesGel electrophoresisBasic proteinMajor classesRNA
1992
Viral small nuclear ribonucleoproteins bind a protein implicated in messenger RNA destabilization.
Myer VE, Lee SI, Steitz JA. Viral small nuclear ribonucleoproteins bind a protein implicated in messenger RNA destabilization. Proceedings Of The National Academy Of Sciences Of The United States Of America 1992, 89: 1296-1300. PMID: 1311093, PMCID: PMC48436, DOI: 10.1073/pnas.89.4.1296.Peer-Reviewed Original ResearchConceptsSmall nuclear ribonucleoproteinNuclear ribonucleoproteinCertain cellular mRNAsMessenger RNA destabilizationHerpesvirus saimiriNumber of protooncogenesHSUR 1HSURs 1Rapid degradationSmall RNAsU RNARNA destabilizationCellular mRNAsMarmoset T lymphocytesAbundant viral transcriptHost proteinsUntranslated regionAUUUA motifsExhibit sequencesViral transcriptsPrimate virusesViral transformationUnstable messagesProteinRibonucleoprotein
1991
Three pseudogenes for human U13 snRNA belong to class III
Baserga S, Yang X, Steitz J. Three pseudogenes for human U13 snRNA belong to class III. Gene 1991, 107: 347-348. PMID: 1748306, DOI: 10.1016/0378-1119(91)90340-h.Peer-Reviewed Original ResearchEAP, a highly conserved cellular protein associated with Epstein‐Barr virus small RNAs (EBERs).
Toczyski DP, Steitz JA. EAP, a highly conserved cellular protein associated with Epstein‐Barr virus small RNAs (EBERs). The EMBO Journal 1991, 10: 459-466. PMID: 1846807, PMCID: PMC452667, DOI: 10.1002/j.1460-2075.1991.tb07968.x.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceB-LymphocytesBase SequenceCell LineCell Transformation, ViralCloning, MolecularDNAHerpesvirus 4, HumanHumansMolecular Sequence DataPolymerase Chain ReactionProteinsRibonucleoproteinsRibonucleoproteins, Small NuclearRibosomal ProteinsRNA-Binding ProteinsRNA, Small NuclearRNA, ViralSequence Homology, Nucleic Acid
1989
Each of the conserved sequence elements flanking the cleavage site of mammalian histone pre-mRNAs has a distinct role in the 3'-end processing reaction.
Mowry KL, Oh R, Steitz JA. Each of the conserved sequence elements flanking the cleavage site of mammalian histone pre-mRNAs has a distinct role in the 3'-end processing reaction. Molecular And Cellular Biology 1989, 9: 3105-3108. PMID: 2779556, PMCID: PMC362782, DOI: 10.1128/mcb.9.7.3105.Peer-Reviewed Original Research
1987
Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly.
Rich BE, Steitz JA. Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly. Molecular And Cellular Biology 1987, 7: 4065-4074. PMID: 3323886, PMCID: PMC368077, DOI: 10.1128/mcb.7.11.4065.Peer-Reviewed Original ResearchConceptsL7/L12
1981
Sequence of U1 RNA from Drosophila melanogaster: implications for U1 secondary structure and possible involvement in splicing
Mount S, Steitz J. Sequence of U1 RNA from Drosophila melanogaster: implications for U1 secondary structure and possible involvement in splicing. Nucleic Acids Research 1981, 9: 6351-6368. PMID: 6172778, PMCID: PMC327608, DOI: 10.1093/nar/9.23.6351.Peer-Reviewed Original ResearchConceptsU1 RNAU1 sequenceCultured Drosophila melanogaster cellsDrosophila U1 RNAU1 RNA sequenceDrosophila melanogaster cellsHuman U1 RNASecondary structure modelDNA sequence determinationDonor splice junctionGenomic clonesDrosophila melanogasterSplicing reactionRNA moleculesU1 snRNPsConsensus sequenceSplice junctionsRNA sequencesNucleotides 3Sequence determinationSecondary structureRNASplicingMolecular interactionsSequence