EBI2 mediates B cell segregation between the outer and centre follicle
Pereira JP, Kelly LM, Xu Y, Cyster JG. EBI2 mediates B cell segregation between the outer and centre follicle. Nature 2009, 460: 1122-1126. PMID: 19597478, PMCID: PMC2809436, DOI: 10.1038/nature08226.Peer-Reviewed Original ResearchConceptsB cellsAntibody responseEpstein-Barr virus infectionOrphan G protein-coupled receptorOuter follicleB cell segregationNormal B cell proliferationDefective antibody responsesB cell positioningGerminal center B cellsActivated B cellsB cell proliferationG protein-coupled receptorsLymphoid folliclesFollicle centersT cellsVirus infectionInterfollicular regionsMice LackingEBI2FolliclesMolecular cuesReceptorsCellsCorrect positioning