2011
EBI2 Guides Serial Movements of Activated B Cells and Ligand Activity Is Detectable in Lymphoid and Nonlymphoid Tissues
Kelly LM, Pereira JP, Yi T, Xu Y, Cyster JG. EBI2 Guides Serial Movements of Activated B Cells and Ligand Activity Is Detectable in Lymphoid and Nonlymphoid Tissues. The Journal Of Immunology 2011, 187: 3026-3032. PMID: 21844396, PMCID: PMC3169736, DOI: 10.4049/jimmunol.1101262.Peer-Reviewed Original ResearchConceptsActivated B cellsB cellsAb responsesNonlymphoid tissuesCCR7-dependent mannerSecondary lymphoid organsDependent Ab responsesB cell migrationLigand activityCCR7 downregulationLymphoid organsFollicular regionsEBI2Outer follicleT zoneCD40 engagementCell linesLipid ligandsLymphoidCell migrationGene 2CellsTissueSerial movementsEarly wave
2010
A Role for S1P and S1P1 in Immature-B Cell Egress from Mouse Bone Marrow
Pereira JP, Cyster J, Xu Y. A Role for S1P and S1P1 in Immature-B Cell Egress from Mouse Bone Marrow. PLOS ONE 2010, 5: e9277. PMID: 20174580, PMCID: PMC2823786, DOI: 10.1371/journal.pone.0009277.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsB-LymphocytesBone MarrowBromodeoxyuridineCell MovementChemotaxis, LeukocyteFemaleFingolimod HydrochlorideImmunosuppressive AgentsLysophospholipidsMaleMiceMice, Inbred C57BLMice, Inbred CBAMice, KnockoutMice, TransgenicPrecursor Cells, B-LymphoidPropylene GlycolsReceptors, LysosphingolipidReverse Transcriptase Polymerase Chain ReactionSignal TransductionSphingosine
2007
Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate
Pappu R, Schwab SR, Cornelissen I, Pereira J, Regard JB, Xu Y, Camerer E, Zheng YW, Huang Y, Cyster JG, Coughlin SR. Promotion of Lymphocyte Egress into Blood and Lymph by Distinct Sources of Sphingosine-1-Phosphate. Science 2007, 316: 295-298. PMID: 17363629, DOI: 10.1126/science.1139221.Peer-Reviewed Original Research
2005
Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients
Schwab SR, Pereira J, Matloubian M, Xu Y, Huang Y, Cyster JG. Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients. Science 2005, 309: 1735-1739. PMID: 16151014, DOI: 10.1126/science.1113640.Peer-Reviewed Original ResearchMeSH KeywordsAldehyde-LyasesAnimalsB-LymphocytesChemotaxis, LeukocyteEnzyme InhibitorsFood Coloring AgentsHematopoietic Stem CellsImidazolesImmunosuppressive AgentsLymphLymph NodesLymphoid TissueLymphopeniaLysophospholipidsMiceMice, Inbred C57BLPyridoxineReceptors, LysosphingolipidRNA InterferenceSphingosineThymus GlandT-LymphocytesVitamin B 6