2023
Mature B cells and mesenchymal stem cells control emergency myelopoiesis
Lim V, Feng X, Miao R, Zehentmeier S, Ewing-Crystal N, Lee M, Tumanov A, Oh J, Iwasaki A, Wang A, Choi J, Pereira J. Mature B cells and mesenchymal stem cells control emergency myelopoiesis. Life Science Alliance 2023, 6: e202301924. PMID: 36717247, PMCID: PMC9889502, DOI: 10.26508/lsa.202301924.Peer-Reviewed Original ResearchConceptsMarrow mesenchymal stem cellsSystemic inflammationMature B cellsB cellsEmergency myelopoiesisMesenchymal stem cellsIL-1 receptorBone marrow mesenchymal stem cellsStem cellsMyeloid cell productionMonocyte numbersB lineage cellsCCL2 productionViral infectionLymphotoxin α1β2InflammationReduced survivalLymphopoietic activityMyelopoiesisLymphopoiesisImportant regulatorLTβRCell productionCellsGenetic blocking
2017
Chapter Two A Chemoattractant-Guided Walk Through Lymphopoiesis From Hematopoietic Stem Cells to Mature B Lymphocytes
Lim VY, Zehentmeier S, Fistonich C, Pereira JP. Chapter Two A Chemoattractant-Guided Walk Through Lymphopoiesis From Hematopoietic Stem Cells to Mature B Lymphocytes. Advances In Immunology 2017, 134: 47-88. PMID: 28413023, PMCID: PMC5784265, DOI: 10.1016/bs.ai.2017.02.001.Peer-Reviewed Original ResearchConceptsHematopoietic stem cellsBone marrow parenchymaProgenitor cellsCell motility machinerySpecialized bone marrow nichesMarrow parenchymaStem cellsMultipotent progenitor cellsCommon lymphoid progenitor cellsStem/progenitor cellsBone marrow nicheBone marrow sinusoidsMotility machineryMature B cell poolStem cell factorLymphoid progenitor cellsEndothelial cellsMature B lymphocytesBCR signalingInterleukin-7Multilineage differentiationMarrow nicheHematopoietic cellsCell factorMarrow sinusoids
2015
Inflammatory Cell Migration in Rheumatoid Arthritis: A Comprehensive Review
Nevius E, Gomes AC, Pereira JP. Inflammatory Cell Migration in Rheumatoid Arthritis: A Comprehensive Review. Clinical Reviews In Allergy & Immunology 2015, 51: 59-78. PMID: 26511861, PMCID: PMC5785098, DOI: 10.1007/s12016-015-8520-9.Peer-Reviewed Original ResearchConceptsRheumatoid arthritisOsteoclast differentiationInflammatory cytokinesT lymphocytesOsteoclast precursorsChronic inflammatory autoimmune diseaseMultiple myeloid cellsInflammatory autoimmune diseaseChronic inflammatory diseaseInflammatory cellular infiltrationAdaptive immune responsesKey inflammatory cytokinesInflammatory cell migrationBone-resorbing osteoclastsIL-17Bone erosionAutoimmune diseasesAntibody responseBone resorptionInflammatory diseasesInnate signalsIL-1Immune responseArticular sitesCellular infiltrationImmature B Cell Egress from Bone Marrow Is SOCS3 Independent
Nadrah K, Beck TC, Pereira JP. Immature B Cell Egress from Bone Marrow Is SOCS3 Independent. PLOS ONE 2015, 10: e0136061. PMID: 26274929, PMCID: PMC4537204, DOI: 10.1371/journal.pone.0136061.Peer-Reviewed Original ResearchConceptsB cell subsetsBone marrowBM parenchymaCell subsetsImmature-B cell egressB cell egressImmature B cell subsetsB cell distributionB lymphocyte subsetsCXCR4 desensitizationSuppressor of cytokineLymphocyte subsetsSOCS3 deficiencyPeripheral bloodSOCS3 deletionB lineage cellsB-lineage lymphocytesB cellsB cell developmentCXCR4Cell egressLigand exposureSOCS3Significant differencesHuman cell lines
2011
Oxysterols direct immune cell migration via EBI2
Hannedouche S, Zhang J, Yi T, Shen W, Nguyen D, Pereira JP, Guerini D, Baumgarten BU, Roggo S, Wen B, Knochenmuss R, Noël S, Gessier F, Kelly LM, Vanek M, Laurent S, Preuss I, Miault C, Christen I, Karuna R, Li W, Koo DI, Suply T, Schmedt C, Peters EC, Falchetto R, Katopodis A, Spanka C, Roy MO, Detheux M, Chen YA, Schultz PG, Cho CY, Seuwen K, Cyster JG, Sailer AW. Oxysterols direct immune cell migration via EBI2. Nature 2011, 475: 524-527. PMID: 21796212, PMCID: PMC4297623, DOI: 10.1038/nature10280.Peer-Reviewed Original Research
2010
Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses
Pereira JP, Kelly LM, Cyster JG. Finding the right niche: B-cell migration in the early phases of T-dependent antibody responses. International Immunology 2010, 22: 413-419. PMID: 20508253, PMCID: PMC2877811, DOI: 10.1093/intimm/dxq047.Peer-Reviewed Original ResearchConceptsHumoral immune responseB cellsGerminal centersPlasma cellsImmune responseHigh-affinity plasma cellsHelper T cellsMemory B cellsDistinct stromal cellsB cell positioningB cell migrationSeparate subcompartmentDependent antibodyLymphoid tissueT cellsStromal cellsCell egressT zoneOrphan receptorChemokinesEarly phaseReceptorsCellsRecent studiesTissue