1999
Direct observation of oxidative stress on the cell wall of Saccharomyces cerevisiae strains with atomic force microscopy
de Souza Pereira R, Geibel J. Direct observation of oxidative stress on the cell wall of Saccharomyces cerevisiae strains with atomic force microscopy. Molecular And Cellular Biochemistry 1999, 201: 17-24. PMID: 10630618, DOI: 10.1023/a:1007007704657.Peer-Reviewed Original ResearchConceptsCell wallGroup of yeastsOxidative damageOxidative stressIndustrial strainsMolecular biologySurface proteinsInduced oxidative damageGerman strainsAmerican strainsMM diamideAtomic force microscopyStrainsSaccharomycesYeastBiologyProteinForce microscopyRapid screening processBiotechnologyPore sizeStressSurface poresOxidantsDiamideContinuous detection of extracellular ATP on living cells by using atomic force microscopy
Schneider S, Egan M, Jena B, Guggino W, Oberleithner H, Geibel J. Continuous detection of extracellular ATP on living cells by using atomic force microscopy. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 12180-12185. PMID: 10518596, PMCID: PMC18432, DOI: 10.1073/pnas.96.21.12180.Peer-Reviewed Original ResearchConceptsAtomic force microscopyForce microscopyLiving cellsImportant compoundsSurface of cellsATP concentrationSurface microenvironmentScanning tipExtracellular ATPCell linesMicroscopyPhysiological conditionsPowerful techniqueCellsContinuous detectionBiosensorSurfaceCompoundsActive tipATPConcentrationFuture developmentSoftnessDetectionMicroenvironment
1997
Localization of amiloride-sensitive sodium channels in A6 cells by atomic force microscopy
Smith P, Bradford A, Schneider S, Benos D, Geibel J. Localization of amiloride-sensitive sodium channels in A6 cells by atomic force microscopy. American Journal Of Physiology 1997, 272: c1295-c1298. PMID: 9142855, DOI: 10.1152/ajpcell.1997.272.4.c1295.Peer-Reviewed Original ResearchConceptsAtomic force microscopyHigh-resolution imagingRenal epithelial cellsForce microscopyA6 cellsApical microvilliCell surface distributionBovine renal medullaEpithelial cellsA6 renal epithelial cellsAmiloride-sensitive sodium channelsEpithelial ion channelsColloidal gold particlesApical distributionIon channelsChannel complexGold particlesSodium channelsCellsMicrovilliNonimmune immunoglobulin GUnlabeled cellsMicroscopySurface distributionParticlesSurface dynamics in living acinar cells imaged by atomic force microscopy: Identification of plasma membrane structures involved in exocytosis
Schneider S, Sritharan K, Geibel J, Oberleithner H, Jena B. Surface dynamics in living acinar cells imaged by atomic force microscopy: Identification of plasma membrane structures involved in exocytosis. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 316-321. PMID: 8990206, PMCID: PMC19328, DOI: 10.1073/pnas.94.1.316.Peer-Reviewed Original ResearchConceptsAtomic force microscopePlasma membrane structureForce microscopeLive acinar cellsSecretory vesicle dockingPlasma membrane dynamicsAtomic force microscopyAcinar cellsMembrane structureVesicle dockingCompensatory endocytosisExocytic processForce microscopyFreeze-fracture electron microscopyMembrane dynamicsPlasma membraneFusion poreUltrahigh resolutionIsolated pancreatic acinar cellsPancreatic acinar cellsSurface dynamicsBasolateral regionStimulation of secretionLimited resolutionElectron microscopy
1995
Visualizing life on biomembranes by atomic force microscopy
Oberleithner H, Brinckmann E, Giebisch G, Geibel J. Visualizing life on biomembranes by atomic force microscopy. Kidney International 1995, 48: 923-929. PMID: 8569101, DOI: 10.1038/ki.1995.373.Peer-Reviewed Original ResearchConceptsAtomic force microscopeNear-field microscopeSoft biological samplesAtomic force microscopyPlasma membrane turnoverForce microscopeForce microscopyPore complexRenal epithelial cellsAtomic resolutionNuclear envelopeAFM techniquesExperimental biologistsMembrane turnoverMolecular structureKidney cellsEpithelial cellsBiological samplesMicroscopeCellsBiomembranesRepresentative examplesRecent dataBiologistsMicroscopy