2010
Toxin Mediated Diarrhea in the 21st Century: The Pathophysiology of Intestinal Ion Transport in the Course of ETEC, V. cholerae and Rotavirus Infection
Kopic S, Geibel JP. Toxin Mediated Diarrhea in the 21st Century: The Pathophysiology of Intestinal Ion Transport in the Course of ETEC, V. cholerae and Rotavirus Infection. Toxins 2010, 2: 2132-2157. PMID: 22069677, PMCID: PMC3153279, DOI: 10.3390/toxins2082132.Peer-Reviewed Original ResearchConceptsEpisodes of diarrheaIntestinal ion transportSpecific therapeutic approachesMajor healthcare concernRotavirus infectionTherapeutic approachesV. choleraeCommon enterotoxinInfectious agentsPathophysiological processesInfectious diseasesDiarrheaHealthcare concernCellular mechanismsLethal effectsPathophysiologyYearsInfectionCholeraeRotavirusDiseaseETEC
2003
Cellular Mechanisms and Physiology of Nucleotide and Nucleoside Release from Cells: Current Knowledge, Novel Assays to Detect Purinergic Agonists, and Future Directions
Schwiebert E, Zsembery A, Geibel J. Cellular Mechanisms and Physiology of Nucleotide and Nucleoside Release from Cells: Current Knowledge, Novel Assays to Detect Purinergic Agonists, and Future Directions. Current Topics In Membranes 2003, 54: 31-58. DOI: 10.1016/s1063-5823(03)01002-0.Peer-Reviewed Original ResearchCellular mechanismsMultiple physiological stimuliIntracellular ATP poolATP releaseNovel assaySteady-state extracellular concentrationAdenosine triphosphateComplete cell lysisCell typesPhysiological sourceIntracellular fuelSubsequent ATP releaseATP poolPhysiological mechanismsCell lysisPhysiological stimuliCurrent knowledgeNucleotidesPurinergic agonistsPurinergic receptorsCellsPhysiologyAssaysDetection assaysCell release