2011
The Anion Exchanger Pendrin (SLC26A4) and Renal Acid-base Homeostasis
Wagner CA, Mohebbi N, Capasso G, Geibel JP. The Anion Exchanger Pendrin (SLC26A4) and Renal Acid-base Homeostasis. Cellular Physiology And Biochemistry 2011, 28: 497-504. PMID: 22116363, DOI: 10.1159/000335111.Peer-Reviewed Original ResearchConceptsAcid-base homeostasisAnion exchanger pendrinExchanger pendrinRenal acid-base homeostasisDietary electrolyte intakeSystemic acid-base statusRole of pendrinType BNormal acid-base homeostasisRegulation of pendrinAcid-base statusRenal expressionAngiotensin IIKidney's roleElectrolyte intakePendrin expressionPositive cellsExchanger activityGenetic ablationAdult kidneyPendrinExpressing cellsLuminal poleKidneyHomeostasis
2003
Localization and Regulation of the ATP6V0A4 (a4) Vacuolar H+-ATPase Subunit Defective in an Inherited Form of Distal Renal Tubular Acidosis
Stehberger PA, Schulz N, Finberg KE, Karet FE, Giebisch G, Lifton RP, Geibel JP, Wagner CA. Localization and Regulation of the ATP6V0A4 (a4) Vacuolar H+-ATPase Subunit Defective in an Inherited Form of Distal Renal Tubular Acidosis. Journal Of The American Society Of Nephrology 2003, 14: 3027-3038. PMID: 14638902, DOI: 10.1097/01.asn.0000099375.74789.ab.Peer-Reviewed Original ResearchConceptsDistal renal tubular acidosisRenal tubular acidosisLoop of HenleProximal tubulesTubular acidosisMouse kidneyA4 expressionDistal tubulesDistal convoluted tubuleProtein expression levelsElectrolyte intakeA4 proteinConvoluted tubulesMouse nephron segmentsNephron segmentsApical stainingWestern blottingAcidosisProtein expressionKidneyATPase activityDistal portionHenleExpression levelsTubules