2011
The Anion Exchanger Pendrin (SLC26A4) and Renal Acid-base Homeostasis
Wagner CA, Mohebbi N, Capasso G, Geibel JP. The Anion Exchanger Pendrin (SLC26A4) and Renal Acid-base Homeostasis. Cellular Physiology And Biochemistry 2011, 28: 497-504. PMID: 22116363, DOI: 10.1159/000335111.Peer-Reviewed Original ResearchConceptsAcid-base homeostasisAnion exchanger pendrinExchanger pendrinRenal acid-base homeostasisDietary electrolyte intakeSystemic acid-base statusRole of pendrinType BNormal acid-base homeostasisRegulation of pendrinAcid-base statusRenal expressionAngiotensin IIKidney's roleElectrolyte intakePendrin expressionPositive cellsExchanger activityGenetic ablationAdult kidneyPendrinExpressing cellsLuminal poleKidneyHomeostasis
2002
Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status
Wagner CA, Finberg KE, Stehberger PA, Lifton RP, Giebisch GH, Aronson PS, Geibel JP. Regulation of the expression of the Cl-/anion exchanger pendrin in mouse kidney by acid-base status. Kidney International 2002, 62: 2109-2117. PMID: 12427135, DOI: 10.1046/j.1523-1755.2002.00671.x.Peer-Reviewed Original ResearchConceptsPendrin-positive cellsAcid-base statusPositive cellsBicarbonate secretionMouse kidneyAcid-base transportKnockout mouse modelProtein expression levelsMetabolic alkalosisDeficient dietExchanger pendrinPendrin expressionMouse modelSensorineural deafnessThyroid glandBicarbonate loadPendred syndromeWestern blottingApical membraneInner earPendrin proteinControl levelsKidneyPendrinProtein levels