Direct Effects of Dopamine on Colonic Mucosal pH: Implications for Tonometry
Winter D, O'Sullivan G, Harvey B, Geibel J. Direct Effects of Dopamine on Colonic Mucosal pH: Implications for Tonometry. Journal Of Surgical Research 1999, 83: 62-68. PMID: 10210644, DOI: 10.1006/jsre.1998.5561.Peer-Reviewed Original ResearchConceptsSodium-hydrogen exchangeSplanchnic perfusionIntestinal mucosaLow-dose dopamine infusionBeta-adrenergic receptor blockadeEffects of dopamineSprague-Dawley ratsIntracellular calcium concentrationHepes-buffered Ringer's solutionMucosal crypt cellsFree cytosolic calciumCalcium-sensitive probeSplanchnic vasodilatorTonometric dataDopamine infusionMucosal effectsReceptor blockadeShocked patientsProtein kinase C inhibitionDistal colonGastric mucosaMucosal pHPharmacological agentsDirect effectTonometric measurementsExpression of an extracellular calcium-sensing receptor in rat stomach
Cheng* ‡, Qureshi§ I, Chattopadhyay‡ N, Qureshi§ A, Butters‡ R, Hall∥ A, Cima* R, Rogers∥ K, Hebert∥ S, Geibel§ J, Brown‡ E, Soybel* D, ¶NPS Pharmaceuticals I. Expression of an extracellular calcium-sensing receptor in rat stomach. Gastroenterology 1999, 116: 118-126. PMID: 9869609, DOI: 10.1016/s0016-5085(99)70235-0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceBlotting, NorthernCalciumCells, CulturedDNA, ComplementaryExtracellular SpaceGastric MucosaImmunohistochemistryMolecular Sequence DataMuscle, SmoothParietal Cells, GastricRatsRats, Sprague-DawleyReceptors, Calcium-SensingReceptors, Cell SurfaceReverse Transcriptase Polymerase Chain ReactionRNAStomachTranscription, GeneticConceptsGastric glandsExtracellular calcium-sensing receptorEpithelial cellsCalcium-sensing receptorReverse transcription-polymerase chain reactionGastric surface cellsMammalian gastric mucosaExpression of CARMyenteric neuronsSubmucosal plexusSurface cellsGastric functionPolymerase chain reactionNerve regionRat stomachGastric mucosaGlandular stomachExtracellular Ca2Secretory functionRat parathyroidSystemic Ca2AbstractTextLevels of Ca2CAR expressionStomach