1998
Angiotensin II stimulates vesicular H+-ATPase in rat proximal tubular cells
Wagner C, Giebisch G, Lang F, Geibel J. Angiotensin II stimulates vesicular H+-ATPase in rat proximal tubular cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 9665-9668. PMID: 9689138, PMCID: PMC21396, DOI: 10.1073/pnas.95.16.9665.Peer-Reviewed Original ResearchConceptsAngiotensin IIProximal tubulesIon secretionEffect of AIIRat proximal tubular cellsAngiotensin II stimulatesRemoval of ClPH-sensitive fluorescent dye 2Proximal tubular cellsNa/H exchangerBafilomycin A1Proximal tubule fragmentsTubular cellsBicarbonate reabsorptionHCO3- reabsorptionTubule fragmentsH exchangerATPase activityFluorescent dye 2Proton pump inhibitor bafilomycin A1Intracellular pHTubulesSecretionPresent studyCell pH
1990
Angiotensin II stimulates both Na(+)-H+ exchange and Na+/HCO3- cotransport in the rabbit proximal tubule.
Geibel J, Giebisch G, Boron W. Angiotensin II stimulates both Na(+)-H+ exchange and Na+/HCO3- cotransport in the rabbit proximal tubule. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 7917-7920. PMID: 2172967, PMCID: PMC54862, DOI: 10.1073/pnas.87.20.7917.Peer-Reviewed Original ResearchConceptsAngiotensin IIHCO3- reabsorptionProximal tubulesEffect of AIIS1 proximal tubulesNM angiotensin IIPH-sensitive fluorescent dye 2Rat proximal tubuleRabbit proximal tubuleSuperficial nephronsPotent stimulusBasolateral administrationRabbit kidneyFluorescent dye 2Basolateral solutionBasolateral stepTransporter activityTubulesIonic mechanismsCotransportKidneyAdministrationNephron