2005
The calcium-sensing receptor acts as a modulator of gastric acid secretion in freshly isolated human gastric glands
Dufner MM, Kirchhoff P, Remy C, Hafner P, Müller M, Cheng SX, Tang LQ, Hebert SC, Geibel JP, Wagner CA. The calcium-sensing receptor acts as a modulator of gastric acid secretion in freshly isolated human gastric glands. AJP Gastrointestinal And Liver Physiology 2005, 289: g1084-g1090. PMID: 16109841, DOI: 10.1152/ajpgi.00571.2004.Peer-Reviewed Original ResearchConceptsHuman gastric glandsHistamine-induced activationGastric acid secretionGastric glandsExtracellular divalent cationsParietal cellsAcid secretionIsolated rat gastric glandsRelease of acetylcholineCalcium-sensing receptorEnterochromaffin-like cellsAbsence of histamineExtracellular divalent cation concentrationFunctional CaSRATPase activityVagus nerveNeuronal pathwaysRat gastric glandsFura-2Human patientsCaSRFluo-4Sustained increaseCalcium measurementsHistamine
1994
The Mastomys Gastric Carcinoid: Aspects of Enterochromaff in-Like Cell Function
Modlin I, Lawton G, Tang L, Geibel J, Abraham R, Darr U. The Mastomys Gastric Carcinoid: Aspects of Enterochromaff in-Like Cell Function. Digestion 1994, 55: 31-37. PMID: 7535269, DOI: 10.1159/000201199.Peer-Reviewed Original ResearchConceptsECL cellsHistamine-1 receptor antagonistsGastric carcinoid tumorsCalcium-dependent mechanismBeta-adrenergic stimulationCarcinoid tumorsGastric carcinoidsReceptor antagonistHistamine secretionTumor growthLike cell functionCell functionGenetic propensitySecretionRegulation of growthMastomys rodentsCarcinoidsCellsMuscarinicPharmacotherapySomatostatinAntagonistTumorsHistamine