Mechanism of aldosterone-induced increase of K+ conductance in early distal renal tubule cells of the frog
Wang W, Henderson R, Geibel J, White S, Giebisch G. Mechanism of aldosterone-induced increase of K+ conductance in early distal renal tubule cells of the frog. The Journal Of Membrane Biology 1989, 111: 277-289. PMID: 2557452, DOI: 10.1007/bf01871012.Peer-Reviewed Original ResearchConceptsEarly distal tubule cellsTubule cellsDistal renal tubule cellsFrog kidneyWhole-cell voltage-clamp techniqueRemoval of aldosteronePresence of aldosteroneAldosterone-induced increaseType II channelsDistal tubule cellsOuabain-treated cellsPatch-clamp techniqueRenal tubule cellsVoltage-clamp techniquePresence of furosemideAldosterone treatmentAldosteroneIncubation of cellsKidneyOpen probabilityDistal cellsHrCellsIntracellularComplete absence