2003
Intracellular pH Activates Membrane-Bound Na+/H+ Exchanger and Vacuolar H+-ATPase in Human Embryonic Kidney (HEK) Cells
Lang K, Wagner C, Haddad G, Burnekova O, Geibel J. Intracellular pH Activates Membrane-Bound Na+/H+ Exchanger and Vacuolar H+-ATPase in Human Embryonic Kidney (HEK) Cells. Cellular Physiology And Biochemistry 2003, 13: 257-262. PMID: 14586169, DOI: 10.1159/000074540.Peer-Reviewed Original ResearchConceptsMicroM EIPAIntracellular acidificationFree bath solutionProximal tubule cellsInfluence of intracellularWestern blot analysisTime-dependent mannerTubule cellsHuman embryonic kidney cellsHEK-293 cellsExtruding mechanismHuman embryonic kidney cell line HEK-293NHE3 proteinEmbryonic kidney cellsCell line HEK-293Cytosolic pHKidney cellsBlot analysisAbsence of bicarbonateHEK293 cellsBath solutionEIPAPresent studyActivationCells
1997
Life on biomembranes viewed with the atomic force microscope.
Oberleithner H, Geibel J, Guggino W, Henderson R, Hunter M, Schneider S, Schwab A, Wang W. Life on biomembranes viewed with the atomic force microscope. Wiener Klinische Wochenschrift 1997, 109: 419-23. PMID: 9261980.Peer-Reviewed Original ResearchConceptsAtomic force microscopeForce microscopeNear-field microscopePlasma membrane turnoverSoft biological surfacesPore complexRenal epithelial cellsAtomic resolutionNuclear poresXenopus laevis oocytesNuclear envelopeAFM techniquesExperimental biologistsLaevis oocytesMembrane turnoverKidney cellsEpithelial cellsMicroscopePotassium channelsBirthday candlesBiological surfacesCellsBiomembranesMolecular structureRecent data
1995
Visualizing life on biomembranes by atomic force microscopy
Oberleithner H, Brinckmann E, Giebisch G, Geibel J. Visualizing life on biomembranes by atomic force microscopy. Kidney International 1995, 48: 923-929. PMID: 8569101, DOI: 10.1038/ki.1995.373.Peer-Reviewed Original ResearchConceptsAtomic force microscopeNear-field microscopeSoft biological samplesAtomic force microscopyPlasma membrane turnoverForce microscopeForce microscopyPore complexRenal epithelial cellsAtomic resolutionNuclear envelopeAFM techniquesExperimental biologistsMembrane turnoverMolecular structureKidney cellsEpithelial cellsBiological samplesMicroscopeCellsBiomembranesRepresentative examplesRecent dataBiologistsMicroscopy
1993
Imaging the lamellipodium of migrating epithelial cells in vivo by atomic force microscopy
Oberleithner H, Giebisch G, Geibel J. Imaging the lamellipodium of migrating epithelial cells in vivo by atomic force microscopy. Pflügers Archiv - European Journal Of Physiology 1993, 425: 506-510. PMID: 8134267, DOI: 10.1007/bf00374878.Peer-Reviewed Original ResearchConceptsPlasma membraneCell locomotionNew plasma membraneCell surfacePlasma membrane potentialCanine kidney cell linePlasma membrane integrityMadin-Darby canine kidney (MDCK) cell lineDynamic physiological processesKidney cell lineAlkaline stressInvagination processCytoskeletal elementsMDCK-F cellsPhysiological processesMembrane integrityMembrane turnoverCell linesKidney cellsMembrane potentialEpithelial cellsTurnover processCellsMembranePotential role