The Phytostilbene Resveratrol Induces Apoptosis in INS-1E Rat Insulinoma Cells
Bortolotti C, Kunit T, Moder A, Hufnagl C, Schmidt S, Hartl A, Langelueddecke C, Fürst J, Geibel J, Ritter M, Jakab M. The Phytostilbene Resveratrol Induces Apoptosis in INS-1E Rat Insulinoma Cells. Cellular Physiology And Biochemistry 2009, 23: 245-254. PMID: 19471092, DOI: 10.1159/000218171.Peer-Reviewed Original ResearchConceptsINS-1E rat insulinoma cellsINS-1E cellsApoptotic volume decreaseRat insulinoma cellsAkt phosphorylationInsulinoma cellsCell proliferationProapoptotic effectsInhibitor compound CBasal Akt phosphorylationExposure of phosphatidylserineInduction of apoptosisG0/G1 phaseCaspase activationPlasma membraneOuter leafletCompound CMuM resveratrolG1 phaseCrystal violet stainingApoptotic cellsCell granularityAddition of insulinPhosphorylationMajor target