2003
Demonstration of a functional apical sodium hydrogen exchanger in isolated rat gastric glands
Kirchhoff P, Wagner CA, Gaetzschmann F, Radebold K, Geibel JP. Demonstration of a functional apical sodium hydrogen exchanger in isolated rat gastric glands. AJP Gastrointestinal And Liver Physiology 2003, 285: g1242-g1248. PMID: 12907430, DOI: 10.1152/ajpgi.00165.2003.Peer-Reviewed Original ResearchAmilorideAnimalsBlotting, WesternCell MembraneEnzyme InhibitorsGastric MucosaGuanidinesH(+)-K(+)-Exchanging ATPaseHistamineHydrogen-Ion ConcentrationImmunohistochemistryIn Vitro TechniquesIntracellular MembranesIsoenzymesMethacrylatesOmeprazoleParietal Cells, GastricPerfusionRatsRats, Sprague-DawleySodium-Hydrogen Exchanger 3Sodium-Hydrogen Exchangers
2001
Gap Junctional Channels Regulate Acid Secretion in the Mammalian Gastric Gland
Radebold K, Horakova E, Gloeckner J, Ortega G, Spray D, Vieweger H, Siebert K, Manuelidis L, Geibel J. Gap Junctional Channels Regulate Acid Secretion in the Mammalian Gastric Gland. The Journal Of Membrane Biology 2001, 183: 147-153. PMID: 11696856, DOI: 10.1007/s00232-001-0062-9.Peer-Reviewed Original ResearchConceptsGap junction channelsAdjacent parietal cellsCell communicationJunction channelsFunctional gap junction channelsGap junctional channelsPotential physiological roleLucifer yellow transferGap junctional proteinGastric glandsParietal cellsWestern blot analysisJunctional channelsJunctional proteinsPhysiological roleRapid cellBlot analysisCalcium signalsBasolateral membraneCell microinjectionAcid secretory processTransfer of dyeSecretory processIntact glandsCalcium wave propagationImpaired Hepatocyte Glucose Transport Protein (GLUT2) Internalization in Chronic Pancreatitis
Nathan J, Zdankiewicz P, Wang J, Spector S, Aspelund G, Jena B, Seymour N, Geibel J, Andersen D. Impaired Hepatocyte Glucose Transport Protein (GLUT2) Internalization in Chronic Pancreatitis. Pancreas 2001, 22: 172-178. PMID: 11249072, DOI: 10.1097/00006676-200103000-00010.Peer-Reviewed Original Research
2000
Ouabain-sensitive H,K-ATPase Functions as Na,K-ATPase in Apical Membranes of Rat Distal Colon*
Rajendran V, Sangan P, Geibel J, Binder H. Ouabain-sensitive H,K-ATPase Functions as Na,K-ATPase in Apical Membranes of Rat Distal Colon*. Journal Of Biological Chemistry 2000, 275: 13035-13040. PMID: 10777607, DOI: 10.1074/jbc.275.17.13035.Peer-Reviewed Original Research
1997
Gi regulation of secretory vesicle swelling examined by atomic force microscopy
Jena B, Schneider S, Geibel J, Webster P, Oberleithner H, Sritharan K. Gi regulation of secretory vesicle swelling examined by atomic force microscopy. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 13317-13322. PMID: 9371843, PMCID: PMC24306, DOI: 10.1073/pnas.94.24.13317.Peer-Reviewed Original ResearchConceptsSecretory vesicle membraneVesicle swellingSecretory vesiclesPlasma membraneVesicle fusionVesicle membraneSecretory vesicle swellingSecretory vesicle fusionConfocal microscopyZymogen granulesCell plasma membraneVesicle volumeHeterotrimeric guanineHeterotrimeric GTPZymogen granule sizeGTPase activityAlpha subunitMolecular mechanismsRegulatory rolePresence of GTPExocytotic processMastoparan analogsProteinGi proteinsMas7LOCALIZATION OF SH‐PTP1 TO SYNAPTIC VESICLES: A POSSIBLE ROLE IN NEUROTRANSMISSION
JENA B, WEBSTER P, GEIBEL J, VAN DEN POL A, SRITHARAN K. LOCALIZATION OF SH‐PTP1 TO SYNAPTIC VESICLES: A POSSIBLE ROLE IN NEUROTRANSMISSION. Cell Biology International 1997, 21: 469-476. PMID: 9451803, DOI: 10.1006/cbir.1997.0185.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlotting, WesternHypothalamusIntracellular Signaling Peptides and ProteinsMicroscopy, ImmunoelectronNerve Tissue ProteinsNeuronsPhosphorylationProtein Processing, Post-TranslationalProtein Tyrosine Phosphatase, Non-Receptor Type 11Protein Tyrosine Phosphatase, Non-Receptor Type 6Protein Tyrosine PhosphatasesProto-Oncogene Proteins pp60(c-src)RatsRats, Sprague-DawleySynaptic TransmissionSynaptic VesiclesSynaptophysin